Aminoguanidine

HCID 2146CAS 79-17-4

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Basic information

Standard SMILES: NN=C(N)N
InChIKey: HAMNKKUPIHEESI-UHFFFAOYSA-N
Molecular formula: CH6N4
Average molar mass: 74.09 g/mol
Monoisotopic mass: 74.05924619

Overview

Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.

Names & identifiers

Preferred name: Aminoguanidine
IUPAC: 2-aminoguanidine
English name: Aminoguanidine
Molecular formula: CH6N4
Molecular weight: 74.09

Names & synonyms

aminoguanidinePimagedineHydrazinecarboximidamide79-17-4Guanyl hydrazineMonoaminoguanidineAminate baseImino semicarbazide1-aminoguanidinepimagedinaSCQ4EZQ113DTXSID5040964

Show more names

Aids030897Aids-030897N-AminoguanidineAminoguanidine (ag)Ribavirin Impurity S

CHEBI:40618pimagedinumRefChem:112042DTXCID3020964201-183-12-aminoguanidinePimagedine [INN]GUANIDINE, AMINO-

Database identifiers

CAS: 79-17-4
PubChem CID: 2146
DTXSID: DTXSID5040964
ChEMBL: CHEMBL225304
ChEBI: CHEBI:40618
UNII: SCQ4EZQ113
EC Number: 201-183-1
Nikkaji: J5.508E

Properties

Computed structural properties

XLogP: -1.5
Topological polar surface area: 90.4 Å²
Hydrogen bond donors: 3
Hydrogen bond acceptors: 2
Rotatable bonds: 0
Heavy atoms: 5
Formal charge: 0
Complexity: 41.6

Experimental & physicochemical properties

DrugsPharmaceuticals -> Listed in ZINC15

Physicochemical properties

Melting point: 182 · 182-185 °C (decomp)
Boiling point: 159.5 · 159.5±23.0 °C(Predicted)
Density: 1.72 · 1.72±0.1 g/cm3(Predicted)
refractive index: 1.666 · 1.6660 (estimate)
pka: 11.08 · 11.08±0.70(Predicted)
FDA UNII: 4 EZQ113 · SCQ4EZQ113

Chemistry & industry

Pharmacology

Mechanism of ActionPimagedine reportedly inhibits the formation of glycosylated proteins (advanced glycosylation end-products) and has other actions including inhibition of aldose reductase.

MeSH Pharmacological ClassificationCompounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Applications

UsesInhibitor (advanced glycosylation end-product formation).

Upstream & downstream products

Upstream raw materials

Downstream products

2-(2,3-Dichlorophenyl)-2-guanidinyliminoacetonitrile Cyclohexanone 3-Pentanone Cyclopentanone Pinacolone 2,6-Dichlorobenzaldehyde 2-Butanone

Suppliers22 total

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]

武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]

武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]

上海遐瑞医药科技有限公司+86 21 61551611

Additional notes · 1 item

DefinitionChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.