Aminoguanidine
Basic information
- CAS
79-17-4- Standard SMILES
NN=C(N)N- InChIKey
HAMNKKUPIHEESI-UHFFFAOYSA-N- Molecular formula
- CH6N4
- Average molar mass
- 74.09 g/mol
- Monoisotopic mass
- 74.05924619
Overview
Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.
Names & identifiers
- Preferred name
- Aminoguanidine
- IUPAC
- 2-aminoguanidine
- English name
- Aminoguanidine
- Molecular formula
- CH6N4
- Molecular weight
- 74.09
Names & synonyms
aminoguanidinePimagedineHydrazinecarboximidamide79-17-4Guanyl hydrazineMonoaminoguanidineAminate baseImino semicarbazide1-aminoguanidinepimagedinaSCQ4EZQ113DTXSID5040964
Show more names
Aids030897Aids-030897N-AminoguanidineAminoguanidine (ag)Ribavirin Impurity S
CHEBI:40618pimagedinumRefChem:112042DTXCID3020964201-183-12-aminoguanidinePimagedine [INN]GUANIDINE, AMINO-
Database identifiers
- CAS
79-17-4- PubChem CID
- 2146
- DTXSID
DTXSID5040964- ChEMBL
CHEMBL225304- ChEBI
CHEBI:40618- UNII
- SCQ4EZQ113
- EC Number
- 201-183-1
- Nikkaji
- J5.508E
Properties
Computed structural properties
- XLogP
- -1.5
- Topological polar surface area
- 90.4 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 5
- Formal charge
- 0
- Complexity
- 41.6
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physicochemical properties
- Melting point
- 182 · 182-185 °C (decomp)
- Boiling point
- 159.5 · 159.5±23.0 °C(Predicted)
- Density
- 1.72 · 1.72±0.1 g/cm3(Predicted)
- refractive index
- 1.666 · 1.6660 (estimate)
- pka
- 11.08 · 11.08±0.70(Predicted)
- FDA UNII
- 4 EZQ113 · SCQ4EZQ113
Chemistry & industry
Pharmacology
Mechanism of ActionPimagedine reportedly inhibits the formation of glycosylated proteins (advanced glycosylation end-products) and has other actions including inhibition of aldose reductase.
MeSH Pharmacological ClassificationCompounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Applications
UsesInhibitor (advanced glycosylation end-product formation).
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
5 records
Compound notes
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