Capromorelin
Basic information
- CAS
193273-66-4- Standard SMILES
CN1N=C2CCN(C(=O)[C@@H](COCc3ccccc3)NC(=O)C(C)(C)N)C[C@@]2(Cc2ccccc2)C1=O- InChIKey
KVLLHLWBPNCVNR-SKCUWOTOSA-N- Molecular formula
- C28H35N5O4
- Average molar mass
- 505.6 g/mol
- Monoisotopic mass
- 505.26890461
Overview
Capromorelin is under investigation in clinical trial NCT00527046 (Effects Of An Oral Growth Hormone Secretagogue In Older Functionally Limited Adults).
Names & identifiers
- Preferred name
- Capromorelin
- IUPAC
- N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamide
- English name
- Capromorelin
- Molecular formula
- C28H35N5O4
- Molecular weight
- 505.61
Names & synonyms
Capromorelin193273-66-4CapimorelinCP-424391capromorelinacapromorelineCP-424,3910MQ44VUN84N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-phenylmethoxypropan-2-yl]-2-amino-2-methylpropanamideDTXSID5057886EluraN-((2R)-1-((3aR)-3a-benzyl-2-methyl-3-oxo-6,7-dihydro-4H-pyrazolo(4,3-c)pyridin-5-yl)-1-oxo-3-phenylmethoxypropan-2-yl)-2-amino-2-methylpropanamide
Show more names
391CP-424CS-1525CP-424391CP-424391, CapromorelinCaprimorelin (Capromorelin)N-[(2R)-1-[(3aR)-3a-benzyl-2-methyl-3-oxo-2H,3H,3aH,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl]-3-(benzyloxy)-1-oxopropan-2-yl]-2-amino-2-methylpropanamide
CAPROMORELINUMRefChem:57558DTXCID6031673Capromorelin [INN]CHEMBL113313Cp 424391UNII-0MQ44VUN84(3ar)-3a-benzyl-2-methyl-5-(2-methylalanyl-o-benzyl-d-seryl)-3-oxo-3,3a,4,5,6,7-hexahydro-2h-pyrazolo[4,3-c]pyridine
Database identifiers
- CAS
193273-66-4- PubChem CID
- 216208
- DTXSID
DTXSID5057886- ChEMBL
CHEMBL113313- UNII
- 0MQ44VUN84
- Nikkaji
- J1.233.873B
Properties
Computed structural properties
- XLogP
- 1.1
- Topological polar surface area
- 117 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 9
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 878
Experimental & physicochemical properties
Animal DrugsFDA approved animal drugs -> Active ingredient
Physicochemical properties
- Density
- 1.25 · 1.25
- pka
- 15 · 15+-.0.46(Predicted)
- FDA UNII
- 0 MQ44VUN84 · 0MQ44VUN84
Chemistry & industry
Pharmacology
ATC CodeQH - Systemic hormonal preparations, excl. sex hormones and insulin
Applications
UsesTreatment and prevention of frailty; treatment of congestive heart failure; treatment of catabolic illness (growth hormone secretagogue).
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Compound notes
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