Basic information
- CAS
5503-08-2- Standard SMILES
C[NH+]1CCC2=C(C1)C(c1ccccc1)c1ccccc12.[Cl-]- InChIKey
QOBFRYKYYDPOEC-UHFFFAOYSA-N- Molecular formula
- C19H20ClN
- Average molar mass
- 297.8 g/mol
- Monoisotopic mass
- 297.1284273
Names & identifiers
- Preferred name
- Phenindamine hydrochloride
- IUPAC
- 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium chloride
- English name
- PhenindaMine Hydrochloride
- Molecular formula
- C19H19N
- Molecular weight
- 261.36086
Names & synonyms
Phenindamine hydrochloride5503-08-22B049A11FH1H-INDENO(2,1-c)PYRIDINE, 2,3,4,9-TETRAHYDRO-2-METHYL-9-PHENYL-, HYDROCHLORIDERefChem:172694Thephorin hydrochloride2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium;chlorideNU 1504 hydrochloride2-Methyl-9-phenyl-2,3,4,9-tetrahydro-1-pyridindene hydrochlorideUNII-2B049A11FH2,3,4,9-Tetrahydro-2-methyl-9-phenyl-1H-indeno(2,1-c)pyridine hydrochloride1,2,3,4-Tetrahydro-2-Methyl-9-phenyl-2-azafluorene Hydrochloride
Show more names
2,3,4,9-Tetrahydro-2-Methyl-9-phenyl-1H-indeno[2,1-c]pyridine Hydrochloride
Database identifiers
- CAS
5503-08-2- PubChem CID
- 21673
Properties
Computed structural properties
- Topological polar surface area
- 4.4 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 1
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 391
Physicochemical properties
- Melting point
- 151 · 151-154 °C
- FDA UNII
- 2 B049A11FH · 2B049A11FH
- Toxicity
- 50 in · LD50 in mice (mg/kg): 88 ±11 i.p., 22.5 ±2.5 i.v., 255 ±21 orally, 270 ±60 s.c.; in rats (mg/kg): 280 ±50 orally; in guinea pigs (mg/kg): 140 ±42 i.p.; in rabbits (mg/kg): 15 ±2.4 i.v., 500 orally; in dogs (mg/kg): 33 i.v. (Lehmann)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 in mice (mg/kg): 88 ±11 i.p., 22.5 ±2.5 i.v., 255 ±21 orally, 270 ±60 s.c.; in rats (mg/kg): 280 ±50 orally; in guinea pigs (mg/kg): 140 ±42 i.p.; in rabbits (mg/kg): 15 ±2.4 i.v., 500 orally; in dogs (mg/kg): 33 i.v. (Lehmann)
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
Applications
UsesPhenindamine Hydrochloride is an antihistaminic.
UsesAntihistaminic.
Suppliers5 total
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
佛山合硕医药科技有限公司15363639686 · [email protected]
Related reactions
0 records
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Compound notes
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