Basic information
- CAS
5560-72-5- Standard SMILES
CN(C)CCCn1c2c(c3ccccc31)CCCCCC2- InChIKey
PLIGPBGDXASWPX-UHFFFAOYSA-N- Molecular formula
- C19H28N2
- Average molar mass
- 284.4 g/mol
- Monoisotopic mass
- 284.2252489
Overview
Iprindole is a member of indoles.
Names & identifiers
- Preferred name
- Iprindole
- IUPAC
- 3-(6,7,8,9,10,11-hexahydrocycloocta[b]indol-5-yl)-N,N-dimethylpropan-1-amine
- English name
- iprindole
- Molecular formula
- C19H28N2
- Molecular weight
- 284.44
Names & synonyms
Iprindole5560-72-5PramindoleGalaturProndolTertranWY-3263IprindolIprindolum69U0IKR8FPNSC-169449DTXSID80204145
Show more names
Iprindole, 10 mM in DMSO6,7,8,9,10,11-Hexahydro-N,N-dimethyl-5H-cyclooct[b]indole-5-propan-1-amine3-(6,7,8,9,10,11-hexahydrocycloocta[b]indol-5-yl)-N,N-dimethylpropan-1-amineInhibitor,Iprindole,inhibit,Serotonin Receptor,5-hydroxytryptamine Receptor,5-HT Receptor
5H-Cyclooct(b)indole-5-propanamine, 6,7,8,9,10,11-hexahydro-N,N-dimethyl-5-(3-(Dimethylamino)propyl)-6,7,8,9,10,11-hexahydro-5H-cyclooct(b)indole5-[3-(Dimethylamino)propyl]-6,7,8,9,10,11-hexahydro-5H-cyclooct[b]indole5H-Cyclooct[b]indole-5-propanamine, 6,7,8,9,10,11-hexahydro-N,N-dimethyl-RefChem:389078DTXCID80126636N06AA13(3-(5H,6H,7H,8H,9H,10H,11H-cycloocta(b)indol-5-yl)propyl)dimethylamine
Database identifiers
- CAS
5560-72-5- PubChem CID
- 21722
- DTXSID
DTXSID80204145- ChEMBL
CHEMBL126224- ChEBI
Properties
Computed structural properties
- XLogP
- 4.6
- Topological polar surface area
- 8.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 4
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 315
Experimental & physicochemical properties
Human DrugsPharmaceuticals
Physicochemical properties
- Boiling point
- 416.93 °C · 416.93°C (rough estimate)
- Density
- 0.9428 · 0.9428 (rough estimate)
- refractive index
- 1.8676 · 1.8676 (estimate)
- storage temp.
- 4 °C, · 4°C, protect from light
- solubility
- 120 mg/mL · DMSO: 120 mg/mL (421.88 mM)
- pka
- 8.2 · pKa 8.2 (Uncertain)
- form
- Oil
- color
- Off-white to light yellow
- Water Solubility
- 0.1 mg/mL · Water: < 0.1 mg/mL (insoluble)
- FDA UNII
- 69 U0IKR8FP · 69U0IKR8FP
- ATC code
- 6 AA13 · N06AA13
Chemistry & industry
Pharmacology
ATC Code
N - Nervous system
QN - Nervous system
MeSH Pharmacological Classification
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
Uses & manufacturing
Use ClassificationPharmaceuticals
Applications
UsesAntidepressant.
UsesChronic administration of atypical antidepressant, Iprindole, was effective in reversing learned helplessness.
Suppliers14 total
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
湖南嘉航医药科技有限公司85521272 18229978283 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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