Basic information
- CAS
35941-65-2- Standard SMILES
CC(CC1c2ccccc2CCc2ccccc21)CN(C)C- InChIKey
ALELTFCQZDXAMQ-UHFFFAOYSA-N- Molecular formula
- C21H27N
- Average molar mass
- 293.4 g/mol
- Monoisotopic mass
- 293.21434987
Overview
Butriptyline is an organic tricyclic compound.
Names & identifiers
- Preferred name
- Butriptyline
- IUPAC
- N,N,2-trimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)propan-1-amine
- English name
- Butriptyline
- Molecular formula
- C21H27N
- Molecular weight
- 293.44578
Names & synonyms
Butriptyline35941-65-2ButriptyleneButriptilinaButriptylinumDTXSID6022715DTXCID902715Z22441975X10,11-Dihydro-N,N,beta-trimethyl-5H-dibenzo(a,d)cycloheptene-5-propylamine10,11-dihydro-N,N,beta-trimethyl-5H-dibenzo(a,d) cycloheptane-5-propylamineAY-2014RefChem:122190
Show more names
Butriptyline (1.0 mg/mL in Methanol)10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propylamine10,11-Dihydro-N,N,-trimethyl-5H-dibenzo[a,d]cycloheptene-5-propanamine5H-Dibenzo[a,d]cycloheptene-5-propanamine, 10,11-dihydro-N,N,β-trimethyl-3-(10,11-Dihydro-5H-dibenzo[A,D][7]annulen-5-yl)-N,N,2-trimethylpropan-1-amine
N06AA15Evadyne15686-37-0AY 62014N,N,2-trimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenyl)propan-1-amineButriptyline (INN)BUTRIPTYLINE [INN](.+-.)-Evadyne
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 5.1
- Topological polar surface area
- 3.2 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 4
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 313
Physicochemical properties
- Boiling point
- 180 · 180-1850C
- Density
- 0.9665 · 0.9665 (rough estimate)
- refractive index
- 1.49 · 1.4900 (estimate)
- pka
- 9.5 · 9.50±0.28(Predicted)
- CAS DataBase Reference
- 35941 · 35941-65-2
- FDA UNII
- 22441975 X · Z22441975X
- RIDADR
- 1851 · 1851
- HazardClass
- 6.1 · 6.1(b)
- PackingGroup
- III
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- ridadr
- 1851
- hazard_class
- 6.1(b)
- packing_group
- III
Chemistry & industry
Pharmacology
ATC Code
N - Nervous system
QN - Nervous system
MeSH Pharmacological Classification
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
Applications
UsesAntidepressant
Upstream & downstream products
Upstream raw materials
Suppliers8 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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