8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]quinolin-2(1H)-one

HCID 21880641
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
530084-74-3
Standard SMILES
CC(C)(C)[Si](C)(C)OC(CBr)c1ccc(OCc2ccccc2)c2[nH]c(=O)ccc12
InChIKey
JQJUYDQHSZTDDO-UHFFFAOYSA-N
Molecular formula
C24H30BrNO3Si
Average molar mass
488.5 g/mol

Names & identifiers

Preferred name
8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]quinolin-2(1H)-one
IUPAC
5-[2-bromo-1-[tert-butyl(dimethyl)silyl]oxyethyl]-8-phenylmethoxy-1H-quinolin-2-one
English name
(8-(benzyloxy)-5-[(1R)-2-broMo-1-{[tert-butyl(diMethyl)silyl]oxy}ethyl]quinolin-2(1H)-one )
Molecular formula
C24H30BrNO3Si
Molecular weight
488.49

Names & synonyms

530084-74-35-[2-bromo-1-[tert-butyl(dimethyl)silyl]oxyethyl]-8-phenylmethoxy-1H-quinolin-2-one8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]quinolin-2(1H)-oneC24H30BrNO3SiSCHEMBL776314JQJUYDQHSZTDDO-UHFFFAOYSA-NFWA08474SB179968-(benzyloxy)-5-[(1R)-2-bromo-1-[(tert-butyldimethylsilyl)oxy]ethyl]-1,2-dihydroquinolin-2-one5-(2-bromo-1-(tert-butyl-dimethyl-silanyloxy)-ethyl)-8-benzyloxy-1H-quinolin-2-one5-[(1R)-2-bromo-1-[tert-butyl(dimethyl)silyl]oxyethyl]-8-phenylmethoxy-1H-quinolin-2-one8-benzyloxy-5-[2-bromo-1-[tert-butyl(dimethyl)silyl]oxy-ethyl]-1H-quinolin-2-one
Show more names
8-(benzyloxy)-5-[(1R)-2-bromo-1-{[tert-butyl(dimethyl)silyl]...8-Benzyloxy-5-[(R)-2-bromo-1-[(tert-butyldimethylsilyl)oxy]ethyl]-1H-quinolin-2-one(S)-8-(benzyloxy)-5-(2-bromo-1-((tert-butyldimethylsilyl)oxy)ethyl)quinolin-2(1H)-one(R)-8-(benzyloxy)-5-(2-bromo-1-((tert-butyldimethylsilyl)oxy)ethyl)quinolin-2(1H)-one(8-(benzyloxy)-5-[(1R)-2-broMo-1-{[tert-butyl(diMethyl)silyl]oxy}ethyl]quinolin-2(1H)-one )ICM-II_[(R)-8-(benzyloxy)-5-(2-bromo-1-((tert-butyl dimethylsilyl) oxy) ethyl) quinolin-2(1H)-one]2(1H)-Quinolinone, 5-[(1R)-2-bromo-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-8-(phenylmethoxy)-

Database identifiers

CAS
530084-74-3
PubChem CID
21880641
EC Number
610-930-4

Properties

Computed structural properties

Topological polar surface area
47.6 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
3
Rotatable bonds
8
Heavy atoms
30

Physicochemical properties

Boiling point
571.4 · 571.4±50.0 °C(Predicted)
Density
1.237 · 1.237±0.06 g/cm3(Predicted)
pka
10.75 · 10.75±0.70(Predicted)
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
302 · H302-H315-H319-H335

Safety & regulation

Safety data

Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H302-H315-H319-H335
Precautionary statements
P280-P305+P351+P338

Chemistry & industry

Applications · 1 item

Uses8-Benzyloxy-5-[(R)-2-bromo-1-(tertbutyldimethylsilyloxy)ethyl]-1H-quinolinone is a reagent used in the preparation of qumuclidinyk carbamate and related derivatives displaying β2 adrenergic agonistic and M3 muscarinic antagonistic activities.

Upstream & downstream products

Suppliers16 total

陕西缔都新材料有限公司81124267 17392282731 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
大赛璐药物手性技术（上海）有限公司021-50460086-9 15921403865 · [email protected]

Related reactions

17 records
New reaction record

Compound notes

Loading…