N-(4-Methyl-2-pyridyl)acetamide

HCID 220485

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Basic information

CAS: 5327-32-2
Standard SMILES: CC(=O)Nc1cc(C)ccn1
InChIKey: QGZHGSGLCZEGHA-UHFFFAOYSA-N
Molecular formula: C8H10N2O
Average molar mass: 150.18 g/mol
Monoisotopic mass: 150.07931294

Names & identifiers

Preferred name: N-(4-Methyl-2-pyridyl)acetamide
IUPAC: N-(4-methyl-2-pyridinyl)acetamide
English name: 2-Acetylamino-4-methylpyridine
Molecular formula: C8H10N2O
Molecular weight: 150.18

Names & synonyms

N-(4-methyl-2-pyridyl)acetamideRefChem:827791803-944-95327-32-2N-(4-methylpyridin-2-yl)acetamide2-acetamido-4-picoline2-Acetylamino-4-methylpyridine2-acetamido-4-methylpyridineMFCD00234432N-(4-methyl-pyridin-2-yl)-acetamideNSC3314N-(4-methyl-2-pyridinyl)acetamide

Show more names

Zinc003310982-Acetamido-4-picoline, 95%2-Acetylamino-4-methylpyridine98%N-(4-Methyl-2-pyridinyl)-AcetaMide2-Acetylamino-4-methylpyridine 98%

ACETAMIDE, N-(4-METHYL-2-PYRIDINYL)-4-Picoline, 2-acetamido-SCHEMBL914754-methyl-2-acetylaminopyridineSCHEMBL2642663DTXSID50277644QGZHGSGLCZEGHA-UHFFFAOYSA-NNSC 3314

Database identifiers

CAS: 5327-32-2
PubChem CID: 220485
DTXSID: DTXSID50277644
EC Number: 803-944-9
Nikkaji: J454.762D

Properties

Computed structural properties

XLogP: 0.7
Topological polar surface area: 42 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 2
Rotatable bonds: 1
Heavy atoms: 11
Formal charge: 0
Complexity: 147

Physicochemical properties

Melting point: 90 · 90-94
Boiling point: 343.1 · 343.1±22.0 °C(Predicted)
Density: 1.137 · 1.137±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 13.82 · 13.82±0.70(Predicted)
form: powder to crystal
color: White to Almost white
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H319
Precautionary statements: 305 · P305+P351+P338
Hazard Codes: Xi,Xn
Risk Statements: 22 · 22-36-36/37/38
Safety Statements: 26 · 26-36/37/39
WGK Germany: 3 · 3
Hazard Note: Irritant/Keep Cold
HazardClass: IRRITANT
HS Code: 29333990 · 29333990

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (97.4%): Harmful if swallowed [Warning Acute toxicity, oral]

P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (97.4%)

Safety data

wgk: 3
hs_code: 29333990
risk_code: 22-36-36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi,Xn
hazard_note: Irritant/Keep Cold
safety_code: 26-36/37/39
hazard_class: IRRITANT
Hazard statements: H302-H319
Precautionary statements: P305+P351+P338

Chemistry & industry

Applications · 1 item

Uses2-Acetylamino-4-methylpyridine is a chemical reagent used in the synthesis of potent inhibitors of Eimeria tenalla cGMP-dependant protein kinase as antiparasitic agents. Also used in the 1-pot synthesis of difluoromethyl-2-pyridone derivatives.