Basic information
- CAS
5968-88-7- Standard SMILES
O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[Mn+3]- InChIKey
XMLHTAFIAXPIDG-UHFFFAOYSA-K- Molecular formula
- C6H5MnO7
- Average molar mass
- 244.04 g/mol
- Monoisotopic mass
- 243.941571
Overview
Manganese citrate is a chemical compound of manganese. Manganese is a naturally occurring metal with the symbol Mn and the atomic number 25. It does not occur naturally in its pure form, but is found in many types of rocks in combination with other substances such as oxygen, sulfur, or chlorine. Manganese occurs naturally in most foods and small amounts are needed to stay healthy, as manganese ions act as cofactors for a number of enzymes. (L228, L229)
Names & identifiers
- Preferred name
- 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, manganese(3+) salt (1:1)
- IUPAC
- 2-hydroxypropane-1,2,3-tricarboxylate;manganese(3+)
- English name
- Manganese(III) citrate
- Molecular formula
- C6H8MnO7
- Molecular weight
- 247.06
Names & synonyms
manganic citrate5968-88-7MANGANESE(III) CITRATE1,2,3-Propanetricarboxylic acid, 2-hydroxy-, manganese(3+) salt (1:1)TC17243R3GMANGANESE MONOCITRATEDTXSID20884208RefChem:71397DTXCID6010236632-hydroxypropane-1,2,3-tricarboxylate;manganese(3+)SCHEMBL362818UNII-TC17243R3G
Show more names
Citric acid manganese(3+) salt (1:1)2-hydroxypropane-1,2,3-tricarboxylate,manganese(3+)
orb3235910AKOS025310172GS-3617manganese(3+) 2-hydroxypropane-1,2,3-tricarboxylateQ27289892
Database identifiers
- CAS
5968-88-7- PubChem CID
- 22274
- DTXSID
DTXSID20884208- UNII
- TC17243R3G
Properties
Computed structural properties
- Topological polar surface area
- 141 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 2
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 211
Experimental & physicochemical properties
Chemical ClassesOther Uses -> Food Additives
Color/FormWhite powder
SolubilitySoluble in water in presence of sodium citrate
Physical DescriptionWhite solid; [Hawley]
Physicochemical properties
- FDA UNII
- 17243 R3G · TC17243R3G
- EPA Substance Registry System
- 1 · 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, manganese(3+) salt (1:1) (5968-88-7)
- TSCA
- TSCA listed
- Hazardous Substances Data
- 5968 · 5968-88-7(Hazardous Substances Data)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Regulatory Information1,2,3-Propanetricarboxylic acid, 2-hydroxy-, manganese(3+) salt (1:1): Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryGenerally regarded as safe (GRAS) for use in foods; Manganese is poorly absorbed after ingestion, and acute toxicity is rare. [HSDB] See Manganese and linked occupational diseases.
FDA Requirements
Substance added directly to human food affirmed as generally recognized as safe (GRAS).
Trace minerals added to animal feeds. These substances added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. Element: Manganese; Source compound: manganese citrate (soluble). (All substances listed may be in anhydrous or hydrated form.) /Manganese citrate (soluble)/
Special Reports
USEPA; Locating and Estimating Air Emissions from Sources of Manganese (1985) EPA-450/4-84-007h
USEPA; Health Assessment Document: Manganese (1984) EPA-600/8-83-013F
WHO; Environ Health Criteria: Manganese (1981)
WHO; Environ Health Criteria: Manganese-Executive Summary (1981)
OSHA StandardsPermissible Exposure Limit: Table Z-1 Ceiling value: 5 mg/cu m. /Manganese cmpd (as Mn)/
Atmospheric Standards
Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Manganese citrate is included on this list.
... Substances for which a Federal Register notice has been published that included consideration of the serious health effects, including cancer, form ambient air exposure to the substance. Manganese (50 FR 32627; Aug. 13, 1985) is included on this list. /Manganese/
Chemistry & industry
Pharmacology
Metabolism/Metabolites
Manganese is absorbed mainly via ingestion, but can also be inhaled. It binds to alpha-2-macroglobulin, albumin, or transferrin in the plasma and is distributed to the brain and all other mammalian tissues, though it tends to accumulate more in the liver, pancreas, and kidney. Manganese is capable of existing in a number of oxidation states and is believed to undergo changes in oxidation state within the body. Manganese oxidation state can influence tissue toxicokinetic behavior, and possibly toxicity. Manganese is excreted primarily in the faeces. (L228)
Uses & manufacturing
Uses
Used as feed and food additive and dietary supplement; [Hawley]
Farming (Feed Additives) [Category: Industry]
Feed additive, food additive, and dietary supplement
Methods of ManufacturingAction of citric acid on manganese hydroxide
General Manufacturing Information1,2,3-Propanetricarboxylic acid, 2-hydroxy-, manganese(3+) salt (1:1): INACTIVE
Suppliers10 total
陕西缔都化学有限公司029-029-81123119 17391733320 · [email protected]
湖北兴琰新材料科技有限公司13129948835 · [email protected]
长沙晶康新材料科技有限公司0731-85118349 18874718518 · [email protected]
湖北海嘉生物科技有限公司15071111164 · [email protected]
Shaanxi Dideu New Materials Co. Ltd
Related reactions
1 records
Compound notes
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