Glycine Hydrochloride

HCID 22316

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Basic information

CAS
6000-43-7
Standard SMILES
Cl.NCC(=O)O
InChIKey
IVLXQGJVBGMLRR-UHFFFAOYSA-N
Molecular formula
C2H5NO2.ClH
Average molar mass
111.53 g/mol
Monoisotopic mass
111.00870611

Overview

See also: Glycine (has active moiety).

Names & identifiers

Preferred name
Glycine Hydrochloride
IUPAC
2-aminoacetic acid;hydrochloride

Names & synonyms

Glycine hydrochloride6000-43-7GLYCINE, HYDROCHLORIDEGlycocoll hydrochlorideAminoacetic acid hydrochloride225ZLC74HXDTXSID7064079Hydrochloride, GlycineRefChem:143839DTXCID0042741227-841-82-aminoacetic acid hydrochloride
Show more names
GLYCINE HClGlycinehydrochlorideCCRIS 3355Glycine, hydrochloride (1:1)glycine-hclEINECS 227-841-8UNII-225ZLC74HXMFCD00012872

Database identifiers

CAS
6000-43-7、7490-95-1
PubChem CID
22316
DTXSID
DTXSID7064079
UNII
225ZLC74HX
EC Number
227-841-8

Properties

Computed structural propertiesFilling in

Topological polar surface area
63.3 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
3
Rotatable bonds
1
Heavy atoms
6

Experimental & physicochemical properties

Chemical ClassesBiological Agents -> Amino Acids and Derivatives
Physical DescriptionHygroscopic solid; [Merck Index] White odorless crystalline powder; Hygroscopic; [Alfa Aesar MSDS]

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 33.3% (3 of 9) of reports.

Danger

H314 (33.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 9 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 2 items

Chemical: Glycine, hydrochloride

Status: Active Update: 29-05-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/23884

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
Hazards SummaryCauses altered sleep time (including change in righting reflex), ataxia, and dyspnea in oral lethal-dose studies of rats; [RTECS] May cause irritation; [Alfa Aesar MSDS] See Glycine.
Hazard Classes and CategoriesSkin Corr. 1B (33.3%)

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationSubstances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.

Uses & manufacturing

UsesUsed as a buffer and reagent in organic chemistry; [Merck Index]
General Manufacturing InformationGlycine, hydrochloride (1:1): ACTIVE

Related reactions

12 records

Compound notes

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CAS 6000-43-7 Glycine Hydrochloride (HCID 22316)|Huagongshe