Dalcaine
Basic information
- CAS
6108-05-0- Standard SMILES
CC[NH+](CC)CC(=O)Nc1c(C)cccc1C.O.[Cl-]- InChIKey
YECIFGHRMFEPJK-UHFFFAOYSA-N- Molecular formula
- C14H25ClN2O2
- Average molar mass
- 288.81 g/mol
- Monoisotopic mass
- 288.1604557
Overview
Lidocaine hydrochloride monohydrate is the monohydrate form of lidocaine hydrochloride. It has a role as a local anaesthetic and an anti-arrhythmia drug. It contains a lidocaine hydrochloride.
Names & identifiers
- Preferred name
- Dalcaine
- IUPAC
- [2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;chloride;hydrate
- English name
- Lidocaine hydrochloride
- Molecular formula
- C14H25ClN2O2
- Molecular weight
- 288.82
Names & synonyms
DalcaineXylocardCHEBI:60791AKOS026750039ST51039045[2-(2,6-dimethylanilino)-2-oxoethyl]-diethylazanium;chloride;hydrate2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide, oxamethane, chlorideLINOCAINE HYDROCHLORIDELINOCAINE HCLLinocaine hydrochlorLinocaine hydrochloride monohydrateLignocaine hydrochloride monohydrate
Show more names
Linocaine hydrochloride(lidocaine HCL)2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride hydrate2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrate hydrochlorideACETAMIDE,2-(DIETHYLAMINO)-N-(2,6-DIMETHYLPHENYL)-MONOHYDROCHLORIDE, MONOHYDRATEdolicaine
Database identifiers
- CAS
6108-05-0- PubChem CID
- 22483
- ChEBI
CHEBI:60791
Properties
Computed structural properties
- Topological polar surface area
- 34.5 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 228
Experimental & physicochemical properties
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Physicochemical properties
- Melting point
- 75 · 75-79℃
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: soluble
- form
- solid
- color
- white
- Water Solubility
- Soluble in water (50 mg/ml), chloroform, ethanol, and benzene. Insoluble in diethyl ether.
- Major Application
- pharmaceutical (small molecule)
- InChI
- InChI=1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
- InChIKey
- YECIFGHRMFEPJK-UHFFFAOYSA-N
- SMILES
- C1(C(C)=CC=CC=1C)NC(=O)CN(CC)CC.O.Cl
- LogP
- 2.359 · 2.359 (est)
- CAS DataBase Reference
- 6108 · 6108-05-0(CAS DataBase Reference)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- tsca
- Yes
- rtecs
- AN7700000
- ridadr
- UN 2811 6.1/PG 3
- hs_code
- 2924296000
- risk_code
- 22
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- Xn
- safety_code
- 36
- hazard_class
- 6.1
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- Hazard statements
- H301
- Hazard Classifications
- Acute Tox. 3 Oral
- Precautionary statements
- P301+P330+P331+P310
Chemistry & industry
Applications
UsesLinocaine hydrochloride is a fast voltage-gated sodium channel blocker that used in Local anesthesia and heart rhythm disorders. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine.
Additional notes
DefinitionChEBI: Linocaine hydrochloride is the monohydrate form of lidocaine hydrochloride. It is a local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of Procaine but its duration of action is shorter than that of bupivacaine or prilocaine.
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…