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3-Methylamino-4-methylphenol

HCID 22639
NotesReactions
Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
6265-13-0
Standard SMILES
CNc1cc(O)ccc1C
InChIKey
QQOKUOJOGXTCMN-UHFFFAOYSA-N
Molecular formula
C8H11NO
Average molar mass
137.18 g/mol
Monoisotopic mass
137.08406397

Overview

3-methylamino-4-methylphenol is a crystalline solid.

Names & identifiers

Preferred name
3-Methylamino-4-methylphenol
IUPAC
4-methyl-3-(methylamino)phenol
English name
4-methyl-3-(methylamino)phenol
Molecular formula
C8H11NO
Molecular weight
137.18

Names & synonyms

3-METHYLAMINO-4-METHYLPHENOL4-methyl-3-methylaminophenolp-Cresol, 3-(methylamino)-RefChem:5041223-(METHYLAMINO)-P-CRESOL4-HYDROXY-2-METHYLAMINOTOLUENE4-methyl-3-(methylamino)phenol6265-13-03-(Methylamino)-4-methylphenolPhenol, 4-methyl-3-(methylamino)-MFCD16998495SCHEMBL8504632
Show more names
DTXSID3074866AKOS006348542MB36159AS-94021CS-0187035C75943F626531

Database identifiers

CAS
6265-13-0
PubChem CID
22639
DTXSID
DTXSID3074866

Properties

Computed structural properties

XLogP
1.9
Topological polar surface area
32.3 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
1
Heavy atoms
10
Formal charge
0
Complexity
105

Experimental & physicochemical properties

Physical Description3-methylamino-4-methylphenol is a crystalline solid.

Physicochemical properties

Boiling point
281.4 · 281.4±28.0 °C(Predicted)
Density
1.109 · 1.109±0.06 g/cm3(Predicted)
storage temp.
2 · 2-8°C, protect from light, stored under nitrogen
pka
10.44 · 10.44±0.18(Predicted)
Appearance
White to off-white Solid
EPA Substance Registry System
3 · 3-(Methylamino)-4-methylphenol (6265-13-0)
Symbol(GHS)
7 · GHS07
Signal word
Warning
Hazard statements
315 · H315-H319-H335
Precautionary statements
261 · P261-P305+P351+P338

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Hazard information

Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Reactive GroupAmines, Phosphines, and Pyridines
Reactivity Profile · 1 item

Phenols, such as 3-METHYLAMINO-4-METHYLPHENOL, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has pKa = 9.88). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.

Air and Water ReactionsNo rapid reaction with air. No rapid reaction with water.

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Chemistry & industry

Upstream & downstream products

Upstream raw materials

Benzenamine, 5-methoxy-N,2-dimethyl-

Suppliers5 total

武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
杭州迈世腾药物科技有限公司0571-82896630 18969958410 · [email protected]
江西弗莱医药科技有限公司15870833005 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
Jilin Chinese Academy of Sciences-yanshen Technology18143011203 · [email protected]

Related reactions

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Compound notes

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On this pageBasic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
Nonfire Spill ResponseSTORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992)
Personal Protective Equipment (PPE) · 1 item

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Safety data

Signal word
Warning
Symbol(GHS)
GHS07
Hazard statements
H315-H319-H335
Precautionary statements
P261-P305+P351+P338