Basic information
- CAS
36067-73-9- Standard SMILES
CCN1CCc2nc(N)oc2CC1- InChIKey
ZNXAJGZPUQOEDZ-UHFFFAOYSA-N- Molecular formula
- C9H15N3O
- Average molar mass
- 181.23 g/mol
- Monoisotopic mass
- 181.12151211
Overview
Azepexole is a small molecule drug. Azepexole has a monoisotopic molecular weight of 181.12 Da.
Names & identifiers
- Preferred name
- Azepexole
- IUPAC
- 6-ethyl-4,5,7,8-tetrahydro-[1,3]oxazolo[4,5-d]azepin-2-amine
- English name
- Azepexole
- Molecular formula
- C9H15N3O
- Molecular weight
- 0
Names & synonyms
Azepexole36067-73-9AzepexolAzepexolumDTXSID1048419DGB112538OazepoxolBHT 933B HT-933RefChem:116074DTXCID30283926-ethyl-4,5,7,8-tetrahydro-[1,3]oxazolo[4,5-d]azepin-2-amine
Show more names
HT-933B-H-9334,5,7,8-Tetrahydro-6-ethyl-6H-oxazolo[4,5-d]azepine-2-amine2-Amino-6-ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepine4H-Oxazolo(4,5-D)azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-
6-ethyl-5,6,7,8-tetrahydro-4h-oxazolo[4,5-d]azepin-2-amineBHT-9332-Amino-6-ethyl-5,6,7,8-tetrahydro-4H-oxazolo(4,5-d)azepineAzepexol [INN-Spanish]Azepexolum [INN-Latin]Azepexole [INN:BAN]UNII-DGB112538OAZEPEXOLE [INN]
Database identifiers
- CAS
36067-73-9- PubChem CID
- 2277
- DTXSID
DTXSID1048419- ChEMBL
CHEMBL149616- UNII
- DGB112538O
- Nikkaji
- J19.340B
Properties
Computed structural properties
- XLogP
- 0.8
- Topological polar surface area
- 55.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 176
Physicochemical properties
- FDA UNII
- 112538 O · DGB112538O
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that selectively bind to and activate alpha adrenergic receptors.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Drugs used to cause constriction of the blood vessels.
Applications
UsesAzepexole (B-HT 933) is a selective α2 adrenergic inducer with over 300-fold selectivity for α2 adrenergic receptors over α1 adrenergic receptors. Azepexole can be used to study the biological functions of α2 adrenergic receptors and inhibition of related diseases. Azepexole may also play a role in regulating mood and improving cognitive function[1].
Suppliers5 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
南通全益生物科技有限公司+86-0513; 18051384581 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
佛山合硕医药科技有限公司15363639686 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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