Basic information
- CAS
4143-63-9- Standard SMILES
O=c1cc(-c2ccc(O)cc2)oc2ccccc12- InChIKey
SHGLJXBLXNNCTE-UHFFFAOYSA-N- Molecular formula
- C15H10O3
- Average molar mass
- 238.24 g/mol
- Monoisotopic mass
- 238.06299418
Overview
structure in first source
Names & identifiers
- Preferred name
- 4'-Hydroxyflavone
- IUPAC
- 2-(4-hydroxyphenyl)chromen-4-one
- English name
- 4'-Hydroxyflavone
- Molecular formula
- C15H10O3
- Molecular weight
- 238.24
Names & synonyms
4'-Hydroxyflavone4143-63-92-(4-hydroxyphenyl)chromen-4-oneNSC-223578I6VZR0K67RefChem:911752835-257-52-(4-hydroxyphenyl)-4H-chromen-4-oneFlavone, 4'-hydroxy-4H-1-Benzopyran-4-one, 2-(4-hydroxyphenyl)-MFCD00017687CHEMBL327209
Show more names
2-(4-Hydroxyphenyl)-4H-1-benzopyran-4-one
NSC 223574 inverted exclamation marka-Hydroxyflavone2H-1-Benzopyran-2-one, 2-(4-hydroxyphenyl)-UNII-8I6VZR0K674kzqNSC223574''-hydroxyflavone4'-Monohydroxyflavone
Database identifiers
- CAS
4143-63-9- PubChem CID
- 229016
- DTXSID
DTXSID70877680- ChEMBL
CHEMBL327209- UNII
- 8I6VZR0K67
- EC Number
- 835-257-5
- Nikkaji
- J354.016B
Properties
Computed structural properties
- XLogP
- 3.2
- Topological polar surface area
- 46.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 353
Experimental & physicochemical properties
LogP3.2
Collision Cross Section147.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- Melting point
- 269 · 269-270 °C(Solv: ethanol (64-17-5))
- Boiling point
- 425.8 · 425.8±45.0 °C(Predicted)
- Density
- 1.34 · 1.340±0.06 g/cm3(Predicted)
- pka
- 8.41 · 8.41±0.13(Predicted)
- form
- powder to crystal
- color
- Light yellow to Brown
- FDA UNII
- 8 I6VZR0K67 · 8I6VZR0K67
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319
- Precautionary statements
- 264 · P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- hs_code
- 2932.99.9090
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 26-36
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Chemistry & industry
Pharmacology
Metabolism/Metabolites4p-Hydroxyflavone has known human metabolites that include Flavone 4p-O-glucuronide.
Applications
Uses4'-Hydroxyflavone is a flavonoid with antioxidant and prooxidant behaviour. 4'-Hydroxyflavone exhibits inhibitory activity as an anti-tuberculosis agent.
Suppliers48 total
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
成都普睿法药物研发有限公司82633860 18982077548 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉市皇臻生物化工有限公司13795480948 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
上海健超生物科技有限公司15021035486 18081542813 · [email protected]
Related reactions
8 records
Compound notes
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