Epihydrocortisone

HCID 229860

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Basic information

CAS: 566-35-8
Standard SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO
InChIKey: JYGXADMDTFJGBT-MKIDGPAKSA-N
Molecular formula: C21H30O5
Average molar mass: 362.466 g/mol
Monoisotopic mass: 362.20932406

Names & identifiers

Preferred name: Epihydrocortisone
IUPAC: 11alpha,17,21-Trihydroxypregn-4-ene-3,20-dione
English name: 11-alpha-Hydrocortisone
Molecular formula: C21H30O5
Molecular weight: 362.46

Names & synonyms

11-EPIHYDROCORTISONENsc23903Epicortisol11-EPICORTISOLEPI COMPOUND 'F'Epi Compound ‘F’EPI COMPOUND ''F''epi-Hydrocortisone11α-Hydrocortisone11-alpha-Hydrocortisone

Database identifiers

CAS: 566-35-8、60103-17-5
PubChem CID: 229860
DTXSID: DTXSID80858945
ChEBI: CHEBI:178075
UNII: GW7CPD2E7K
Nikkaji: J638.488I

Properties

Physicochemical properties

Melting point: 217 · 217-219 °C
Boiling point: 566.4 · 566.4±50.0 °C(Predicted)
Density: 1.28 · 1.28±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
pka: 12.47 · 12.47±0.70(Predicted)
color: White to Off-White
InChIKey: JYGXADMDTFJGBT-RPEWHVAONA-N
SMILES: [C@@]12([H])CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@@H](O)[C@]1([H])[C@@]3(C)CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,10,13,15,17,27,r|
FDA UNII: 7 CPD2E7K · GW7CPD2E7K

Chemistry & industry

Applications · 2 items

Uses11-Epihydrocortisone is an isomer of Hydrocortisone (H714615), a glucocorticord which functions primarily to increase blood sugar through gluconeogenesis, suppression of immune system and aid in fat, protein and carbohydrate metabolism.

Uses11-Epihydrocortisone (Hydrocortisone EP Impurity M) is an isomer of Hydrocortisone (H714615), a glucocorticord which functions primarily to increase blood sugar through gluconeogenesis, suppression of immune system and aid in fat, protein and carbohydrate metabolism.

Upstream & downstream products

Downstream products

6,9-Difluoropregn-4-ene-11,17,21-triol-3,20-dione17,21-diacetate 9-Bromo-11,17,21-trihydroxypregn-4-ene-3,20-dione17,21-diacetate 9-Bromo-11,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate 9-Fluoropregna-1,4-diene-11,17,21-triol-3,20-dione17,21-diacetate 6,9-Difluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 21-acetate 6-Fluoro-17,21-dihydroxypregna-4,9(11)-diene-3,20-dione 17,21-diacetate 11alpha,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate 9,11-Epoxy-6-fluoro-17,21-dihydroxypregn-4-ene-3,20-dione-17,21-diacetate 6alpha,9-difluoro-11beta,21-dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate 9,11-Epoxypregn-4-ene-17,21-diol-3,20-dione 21-acetate 17,21-Diacetyloxy-9,11-epoxypregn-4-ene-3,20-dione Pregna-4,9(11)-diene-17,21-diol-3,20-dione17,21-diacetate

Suppliers47 total

陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]

安礼特（上海）医药科技有限公司18109805911 · [email protected]

艾吉析科技（上海）有限公司17717235263 · [email protected]

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]

清宁生物（江苏博泉生物科技有限公司）19352250998 · [email protected]

Additional notes

DefinitionChEBI: 11alpha-Hydrocortisone is a 21-hydroxy steroid.

Related reactions

2 records

New reaction record

HRID 1709160As reactantuspto-grants-1990_08

HRID 1709161As reactantuspto-grants-1990_08

Compound notes

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