3-Hydroxypiperidine

HCID 23293CAS 6859-99-0
Substructure searchFind similar structures

Basic information

Standard SMILES
OC1CCCNC1
InChIKey
BIWOSRSKDCZIFM-UHFFFAOYSA-N
Molecular formula
C5H11NO
Average molar mass
101.15 g/mol
Monoisotopic mass
101.08406397

Names & identifiers

Preferred name
3-Hydroxypiperidine
IUPAC
piperidin-3-ol
English name
3-Hydroxypiperidine
Molecular formula
C5H11NO
Molecular weight
101.15

Names & synonyms

3-HydroxypiperidinePiperidin-3-ol6859-99-03-HydroxyhexahydropyridineEINECS 229-957-4NSC 62082RefChem:94384229-957-4BIWOSRSKDCZIFM-UHFFFAOYSA-N3-PIPERIDINOL3-hydroxy piperidineMFCD00014591
Show more names
Benidipine Impurity 173-hydroxyperidineOEM 3-Hydroxypiperidin3-Hydroxypiperidine>3-HYDROXYPIPERIDINE 98%(3R)-3-piperidin-1-iumol
Benidipine Impurity 4(+/-)-3-HYDROXYPIPERIDINENSC-620823-Hydroxypiperadinepiperidine-3-ol(+/-)-3-Piperidinol; (R,S)-3-Hydroxypiperidine; (+/-)-3-Hydroxypiperidine; 3-Hydroxyhexahydropyridine; NSC 62082NSC620823-hydroxy-piperdine

Database identifiers

CAS
6859-99-0
PubChem CID
23293
DTXSID
DTXSID70870212
ChEMBL
CHEMBL22463
UNII
UH54C3N4VL
EC Number
229-957-4
Nikkaji
J100.751C

Properties

Computed structural properties

XLogP
-0.3
Topological polar surface area
32.3 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
0
Heavy atoms
7

Experimental & physicochemical properties

Collision Cross Section123.27 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Physicochemical properties

Melting point
57 · 57-61 °C
Boiling point
67 · 67-69 °C (2 mmHg)
Density
1.016 · 1.016±0.06 g/cm3(Predicted)
Flash point
100 °C · >100°C
storage temp.
2 · 2-8°C
solubility
0.1 g/mL, · ethanol: 0.1 g/mL, clear

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H314 (92.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 51 reports by companies from 7 notifications to the ECHA C&L Inventory.

Hazard information

Regulatory Information · 2 items

Status: Active Update: 30-08-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/20374

3-Piperidinol: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Corr. 1B (92.2%)

Safety data

PPE
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
wgk
3
ridadr
UN 3263 8/PG 2
hs_code
29333990
risk_code
34-20/21/22-36/37/38
Signal word
Danger

Chemistry & industry

Applications

Uses3-Hydroxypiperidine is usually used for Synthesis of unsymmetrical ureas,Synthesis of piperidine nucleoside analogs,Fluorination reactions,Synthesis of substituted pyridines.

General Description3-Hydroxypiperidine can be obtained from the reduction of 3-hydroxypyridine.

Upstream & downstream products

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

208 records
New reaction record

Linked notes

Loading…