metoclopramide hydrochloride anhydrous
Basic information
- CAS
2576-84-3- Standard SMILES
CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC.Cl- InChIKey
RVFUNJWWXKCWNS-UHFFFAOYSA-N- Molecular formula
- C14H23Cl2N3O2
- Average molar mass
- 336.3 g/mol
- Monoisotopic mass
- 335.1167324
Overview
See also: Metoclopramide Hydrochloride (annotation moved to).
Names & identifiers
- Preferred name
- metoclopramide hydrochloride anhydrous
- IUPAC
- 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride
- English name
- 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide dihydrochloride
- Molecular formula
- C14H23Cl2N3O2
- Molecular weight
- 336.26
Names & synonyms
7B1QZY5SWZMetoclopramide hydrochloride anhydrousNSC-354467Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide monohydrochloride4-AMINO-5-CHLORO-N-(2-(DIETHYLAMINO)ETHYL)-O-ANISAMIDE MONOHYDROCHLORIDE4-AMINO-5-CHLORO-N-[2-(DIETHYLAMINO)ETHYL]-2-METHOXYBENZAMIDE MONOHYDROCHLORIDEBenzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy-, monohydrochloride (9CI)Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, monohydrochlorideRefChem:818767Metoclopramide monohydrochlorideRimetin
Show more names
Einecs 219-926-3Metoclopramide 2HClMETOCLOPRAMIDEDIHYDROCHLORIDE,ANHYDROUS4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide dihydrochlorideBenzaMide, 4-aMino-5-chloro-N-[2-(diethylaMino)ethyl]-2-Methoxy-, dihydrochloride
CerucalMetozolv4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide hydrochlorideMetoclopramide (hydrochloride)MLS000069667Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride (1:1)SMR0000584714-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride
Properties
Computed structural properties
- Topological polar surface area
- 67.6 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 7
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 300
Experimental & physicochemical properties
Solubility>50.4 [ug/mL] (The mean of the results at pH 7.4)
Collision Cross Section171.8 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- FDA UNII
- 5 YNA80E9TO · 5YNA80E9TO
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (99%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 99 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory InformationMetoclopramide hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-, monohydrochloride: Environment tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (99%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Applications
UsesMetoclopramide dihydrochloride acts as a dopamine D2 antagonist and is utilized for its antiemetic properties.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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