| GHS classification | DangerH272 (85.3%): May intensify fireoxidizer [Danger Oxidizing liquidsOxidizing solids]H302 (58.2%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (59.6%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (66.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (59.4%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P210, P220, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 443 reports by companies from 25 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
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| Regulatory information | Chemical: Iodic acid (HIO3), potassium saltStatus: Active Update: 01-07-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/13616Iodic acid, potassium salt: Does not have an individual approval but may be used under an appropriate group standard |
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| Other safety information | IMAP assessments - Iodic acid and selected salts: Human health tier II assessment |
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| Fire potential | ...DANGEROUS BECAUSE THEY ARE STRONG OXIDIZERS. IN CONTACT WITH FLAMMABLE OR EVEN COMBUSTIBLE MATERIALS THEY CAN START FIRES. /IODATES/ |
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| Hazards summary | Causes gastrointestinal tract, liver, and kidney injury in high-dose animal experiments[HSDB] |
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| FDA requirements | Substance added directly to human food affirmed as generally recognized as safe (GRAS). |
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| Special Reports | REVIEW OF THE HEALTH ASPECTS OF POTASSIUM IODIDE, POTASSIUM IODATE, & CALCIUM IODATE AS FOOD INGREDIENTS.[LIFE SCIENCES RESEARCH OFFICE/FEDERATION OF AMERICAN SOCIETIES FOR EXPTL BIOLOGYEVALUATION OF THE HEALTH ASPECTS OF POTASSIUM IODIDE, POTASSIUM IODATE, & CALCIUM IODATE AS FOOD INGREDIENTSUSNTIS PB REPORT PB-254 533: 22 PP (1975)] |
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| Hazard Classes and Categories | Ox. Sol. 2 (85.3%)Acute Tox. 4 (58.2%)Skin Irrit. 2 (59.6%)Eye Irrit. 2 (66.8%)STOT SE 3 (59.4%)Acute toxicity (ingestion) - category 4Specific target organ toxicity (single exposure) - category 2Acute toxicity (Oral) - Category 4 |
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| Hazardous Reactivities and Incompatibilities | CAN REACT VIGOROUSLY WITH REDUCING MATERIALSPotentially explosive reaction with charcoal + ozonemetalsarseniccarbonphosphorussulfuralkali metal hydridesalkaline earth metal hydridesantimony sulfidearsenic sulfidecopper sulfidetin sulfidemetal cyanidesmetal thiocyanatesmanganese dioxide. Violent reaction with organic matter. |
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| Disposal methods | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
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| Protective Action Criteria (PAC) | 3.6 [mg/m3]40 [mg/m3]240 [mg/m3] |
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| Adverse effects | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
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| Human Toxicity Excerpts | NO HUMAN INGESTION OF IODATE SALTS CAN BE CITED. /IODATE SALTS/ |
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| Non-Human Toxicity Excerpts | ...IN FASTING DOG...0.2-0.25 G/KG...USUALLY CAUSE/S/ EMESIS, BUT IF THIS IS PREVENTED SIGNS OF ANOREXIA AND PROSTRATION PRECEDE DEATH. NECROTIC LESIONS OF THE LIVER, KIDNEYS AND GASTRIC AND INTESTINAL MUCOSA...POTASSIUM & SODIUM IODATE HAVE ABOUT THE SAME LD50 & PRODUCE DEATH IN ACUTE RENAL FAILURE /IN MICE/...SOMETIMES HEMOGLOBINURIA PRECEDED RENAL SHUTDOWN.POTASSIUM IODATE INDUCED STERILITY IN COPTA MITE (T PUTRESCENTIAE) WHEN GIVEN IN DIET @ 0.25-1.0% CONCN FOR 1-2 WK. FEMALES WERE MORE SUSCEPTIBLE THAN MALES. EGG FORMATION WAS DETRIMENTALLY AFFECTED.POTASSIUM IODATE INDUCED DEFORMED SPIRACLES IN PUPAE WHEN FED TO SILKWORM LARVAE @ 100 PPM IODINE. |
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| Non-Human Toxicity Values | LD50 Mouse ip 136 mg/kg |
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