Basic information
- CAS
7336-40-5- Standard SMILES
COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1[C@@H](N(C)C(C)=O)CC2- InChIKey
AHZFWPXTSZCLDJ-KRWDZBQOSA-N- Molecular formula
- C23H27NO6
- Average molar mass
- 413.5 g/mol
- Monoisotopic mass
- 413.18383758
Names & identifiers
- Preferred name
- N-Methyl-N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamide
- IUPAC
- N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
- English name
- Colchicine, N-methyl-
- Molecular formula
- C23H27NO6
- Molecular weight
- 413.46
Names & synonyms
COLCHICINE, N-METHYL-7336-40-5DTXSID50223606N-Methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]acetamideN-Methyl-N-((7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)acetamideRefChem:1091916DTXCID40146097N-MethylcolchicineN-AcetylcolchamineN-AcetyldemecolcineN-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamideN-Acetylcolcemid
Show more names
N-AcetaminophenN-Acetaminophen, 10 mM in DMSONAcetaminophen,N AcetaminophenN-[(S)-5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-N-methylacetamideAcetamide, N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
NSC 403155BRN 2825013Acetamide, N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-NSC403155Acetamide, N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-CHEMBL89261orb1296897SCHEMBL30662037
Properties
Computed structural properties
- XLogP
- 1.3
- Topological polar surface area
- 74.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 5
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 770
Physicochemical properties
- EWG's Food Scores
- 1 · 1
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
DescriptionA colchicine type alkaloid, N-acetyldemecolcine occurs in both the corms and seeds of Colchicum autumnale, Gloriosa virescens and Littoria modesta. It is separated from the numerous other accompanying bases by column and thin_x0002_layer chromatography. The base is laevorotatory with a specific rotation of [α]D - 2440 (c 1.0, CHC13).
UsesMicromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC50 values of 10.93 and 12.38 μM[1].
Suppliers26 total
成都普瑞法科技开发有限公司+86-028-82633397 18982077548 · [email protected]
成都乐美天医药科技有限公司17308096051 17308096051 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
武汉众志诚生物技术有限公司13628624121 13628604890 · [email protected]
成都普睿法药物研发有限公司82633860 18982077548 · [email protected]
成都普思生物科技股份有限公司028-85370565-229 18080489829 · [email protected]
武汉市皇臻生物化工有限公司13795480948 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
武汉天植生物技术有限公司18607101326 15172504745 · [email protected]
四川精萃天成药物科技有限公司028-87865381 18108190480 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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