Sodium nitrite
NaNO2 · YAXIAOSUANNA · natriumnitrit · NITRITE STANDARD SOLUTION · filmerine · NITRITE STANDARD · NANO2(SODIUM NITRITE · Sodium nitrite standard
Identifiers & Physical Properties
| CAS No. | 7632-00-0 |
|---|---|
| Molecular formula | NaNO2 |
| Average molar mass | 69 g/mol |
| SMILES | O=NO.[Na] |
| PubChem CID | 24188564 |
Chemical & Physical Properties
| Melting point | 271 °C (lit.) |
|---|---|
| Boiling point | 320 °C |
| Density | 2.17g/cm3 |
| Bulk density | 1200kg/m3 |
| Vapor pressure | <0.0001 hPa ( 25 °C) |
| Refractive index | 1.65 |
| Storage conditions | 2-8°C |
| Solubility | aqueous acid: 1 - 2μl acetic acid per ml H2Osoluble820 g/L (20 ºC) |
| Physical state | powder |
| Color | White or colorless |
| Specific gravity | 2.168 |
| Odor | Odorless |
| PH Range | 9 |
| pH | 9 (100g/l, H2O, 20℃) |
| Oxidising Properties | The substance or mixture is classified as oxidizing with the subcategory 3 |
| Sensitivity | Hygroscopic |
| Merck | 14,8648 |
| Stability | Stable. Incompatible with reducing agents, strong oxidizing agents, organics and other flammable materials, finely powdered metals. Contact with combustible material may lead to fire. Hygroscopic. |
| Cosmetics Ingredients Functions | ANTICORROSIVE |
| InChI | 1S/HNO2.Na/c2-1-3/h(H,2,3)/q+1/p-1 |
| InChIKey | LPXPTNMVRIOKMN-UHFFFAOYSA-M |
| SMILES | [Na+].[O-]N=O |
| Toxicology and Carcinogenesis | Toxicology and Carcinogenesis Studies of Sodium Nitrite (CASRN 7632-00-0) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies) |
| Substances Added to Food (formerly EAFUS) | SODIUM NITRITE |
| FDA 21 CFR | 175.105175.300176.170176.180177.1210177.2600178.3570178.3910181.33 |
| CAS DataBase Reference | 7632-00-0(CAS DataBase Reference) |
| EWG's Food Scores | 2-4 |
| FDA UNII | M0KG633D4F |
| ATC code | V03AB08 |
| EPA Substance Registry System | Sodium nitrite (7632-00-0) |
| UNSPSC Code | 85151701 |
| NACRES | NB.61 |
| GHS pictogram | GHS03,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| GHS hazard statements | H301-H319-H361-H362-H370-H341-H400-H272 |
| GHS precautionary statements | P501-P263-P273-P260-P270-P202-P220-P210-P201-P221-P264-P280-P370+P378-P391-P337+P313-P305+P351+P338-P308+P311-P301+P310+P330-P405 |
| Hazard symbols | O,T,N,Xn |
| Risk statements (R) | 8-25-50-22-36/38 |
| Safety statements (S) | 45-61-36-26 |
| UN transport number | UN 1500 |
| Water hazard class (WGK) | 3 |
| RTECS number | RA1225000 |
| F | 10 |
| Autoignition temperature | 914 °F |
| TSCA inventory status | TSCA listed |
| Hazard class | 5.1Acute Tox. 3 OralAquatic Acute 1Eye Irrit. 2Ox. Sol. 3 |
| Packing group | III |
| Customs code | 28341000 |
| Storage class | 5.1B - Oxidizing hazardous materials |
| Hazardous substances data | 7632-00-0(Hazardous Substances Data) |
| Toxicity | LD50 orally in rats: 180 mg/kg (Smyth) |
| REACH registrations | Active |
Safety & Regulations
| F | 10 |
|---|---|
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| RTECS number | RA1225000 |
| UN transport number | UN 1500 |
| Customs code | 28341000 |
| Toxicity | LD50 orally in rats: 180 mg/kg (Smyth) |
| Risk statements (R) | 8-25-50-22-36/38 |
| Signal word | Danger |
| GHS pictogram | GHS03,GHS06,GHS08,GHS09 |
| Hazard symbols | O,T,N,Xn |
| Safety statements (S) | 45-61-36-26 |
| Hazard class | 5.1Acute Tox. 3 OralAquatic Acute 1Eye Irrit. 2Ox. Sol. 3 |
| Storage class | 5.1B - Oxidizing hazardous materials |
| Packing group | III |
| GHS hazard statements | H301-H319-H361-H362-H370-H341-H400-H272 |
| REACH registrations | Active |
| Autoignition temperature | 914 °F |
| GHS precautionary statements | P501-P263-P273-P260-P270-P202-P220-P210-P201-P221-P264-P280-P370+P378-P391-P337+P313-P305+P351+P338-P308+P311-P301+P310+P330-P405 |
| Hazardous substances data | 7632-00-0(Hazardous Substances Data) |
Applications & Uses
Uses
Sodium nitrite is a commonly used meat preservative, particularly in cured meats such as ham, hot dogs, sausages, and bacon. The nitrite ion inhibits the growth of bacteria, particularly Clostridium botulinum, an organism that produces the deadly botulism toxin. Sodium nitrite is also used to treat packages of red meat, such as beef. Blood exposed to the air rapidly produces a brown color, but shoppers much prefer their meat purchases to look bright red.Thus,the meat is treated with sodium nitrite; the nitrite ion is reduced to nitrogen monoxide, which then reacts with the hemoglobin to form a very stable bright red compound.It is true that the nitrite will prevent bacterial growth in this circumstance as well, but these days, the meat is kept at temperatures low enough to inhibit bacteria.To persuade shoppers to prefer brownish rather than red meat will require a lot of re-education. Now that all meats are treated with sodium nitrite, there is concern that the cooking process will cause the nitrite ion to react with amines in the meat to produce nitrosamines,compounds containing the -NNO functional group. These compounds are known to be carcinogenic.However, as long as preserved meats are consumed in moderation, it is generally believed that the cancer risk is minimal.
Description
Sodium nitrite is similar in name and use to sodium nitrate. Both are preservatives used in processed meats, such as salami, hot dogs, and bacon. Sodium nitrite has been synthesized by several chemical reactions that involve the reduction of sodium nitrate. Industrial production of sodium nitrite is primarily by the absorption of nitrogen oxides into aqueous sodium carbonate or sodium hydroxide. Over the years, sodium nitrite has raised some concerns about its safety in foods, but it remains in use and there are indications that it may actually be healthy. Sodium nitrite was developed during the 1960s. In 1977, the US Department of Agriculture (USDA) considered banning it but the USDA’s final ruling on the additive came out in 1984, allowing its use. Studies in the 1990s indicated some adverse effects of sodium nitrite, for instance the potential to cause childhood leukemia and brain cancers. In the late 1990s, the National Toxicity Program (NTP) began a review of sodium nitrite and proposed listing sodium nitrite as a developmental and reproductive toxicant, but a report in 2000 by NTP proposed that sodium nitrite is not a toxic substance and removed it from the list of developmental and reproductive toxicants. It is now believed that it can help with organ transplants and leg vascular problems, while preventing heart attacks and sickle cell disease.
Uses
Sodium Nitrite is the salt of nitrous acid that functions as an antimicrobial agent and preservative. it is a slightly yellow granular powder or nearly white, opaque mass or sticks. it is deliquescent in air. it has a solubility of 1 g in 1.5 ml of water. it is used in meat curing for color fixation and development of flavor. see nitrite.