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Basic information
- CAS
52794-97-5- Standard SMILES
CC(=O)[C@]1(O)Cc2c(O)c3c(c(O)c2[C@@H](OC2CC(N)C(O)C(C)O2)C1)C(=O)c1c(O)cccc1C3=O.Cl- InChIKey
WYVYEIZFAUXWKW-TTYSTUCBSA-N- Molecular formula
- C26H28ClNO10
- Average molar mass
- 549.96 g/mol
- Monoisotopic mass
- 549.14017378
Names & identifiers
- Preferred name
- 3-Acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside--hydrogen chloride (1/1)
- IUPAC
- (1S,3S)-3-Acetyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside--hydrogen chloride (1/1)
- English name
- Carubicin
- Molecular formula
- C26H28ClNO10
- Molecular weight
- 549.96
Names & synonyms
Carminomycin hydrochlorideNsc275649Carubicin HClKarminomycin HClCaminomycin hydrochlorideKarminomycin hydrochloride4-Demethyl daunorubicin hydrochlorideCarminomycin Hydrochloride(Carubicin Hydrochloride)4-Demethyl Daunorubicin Hydrochloride (Carubicin HCl)5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-, hydrochloride (8S-cis)-
Database identifiers
- CAS
52794-97-5- PubChem CID
- 24197838
- DTXSID
DTXSID30967253- ChEMBL
CHEMBL537408
Properties
Physicochemical properties
- alpha
- 20 · D20 +289°
- storage temp.
- 4 °C, · 4°C, away from moisture
- solubility
- 62.5 mg/mL · DMSO : 62.5 mg/mL (113.65 mM; Need ultrasonic)
- pka
- 1 · pKa1 8.00; pKa2 10.16(at 25℃)
- form
- Solid
- color
- Light Red to Red
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 4 V3R166MB3 · 4V3R166MB3
- Toxicity
- 50 in · LD50 in mice (mg/kg): 7.3 orally; 1.3 i.v.; 3.7 s.c. (Goldberg)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 in mice (mg/kg): 7.3 orally; 1.3 i.v.; 3.7 s.c. (Goldberg)
Chemistry & industry
Applications
UsesAntineoplastic. .
UsesKarminomycin Hydrochloride is an antibiotic that potently kills human tumor cells and their multidrug resistant variants. Highly active quinone-containing anticancer drugs. A new anthracycline antineoplastic antibiotic.
Suppliers27 total
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
武汉本杰明医药股份有限公司027-52341919 13545198479 · [email protected]
台州川旭医药科技有限公司[email protected] 15165038510 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
常州翔龙医药科技有限公司18915873328 18915873328 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
武汉多普乐生物医药有限公司+86-02787215551 19945035818 · [email protected]
Related reactions
0 records
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Compound notes
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