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Basic information
- CAS
81012-94-4- Standard SMILES
Nc1nc(Cl)nc2c1ncn2C1OC(CO)C(O)C1O.O- InChIKey
CSVJEVDOHIWPDO-UHFFFAOYSA-N- Molecular formula
- C10H14ClN5O5
- Average molar mass
- 319.705 g/mol
- Monoisotopic mass
- 319.06834623
Names & identifiers
- Preferred name
- 2-Chloro-9-pentofuranosyl-9H-purin-6-amine--water (1/1)
- IUPAC
- 2-Chloro-9-pentofuranosyl-9H-purin-6-amine--water (1/1)
- English name
- 2-Chloroadenosine hemidydrate
- Molecular formula
- C10H14ClN5O5
- Molecular weight
- 319.7
Names & synonyms
2-CHLOROADENOSINE HEMIHYDRATE2-CADO2-CL-ADO2-Chloroadensoine2-CADO, HEMIHYDRATE2-CHLOROADENOSINE HEMIDYDRATE2-chloroadenosine hemidydrate 2(2-Chloroadenosine hemihydrate,97%2-CHLORO-D-ADENOSINE, HEMIHYDRATE2-Chloroadenosine hemidydrate USP/EP/BP
Database identifiers
- CAS
81012-94-4- PubChem CID
- 24211897
- DTXSID
DTXSID80639938- EC Number
- 630-491-2
Properties
Physicochemical properties
- Melting point
- 160 °C · 160 °C (dec.)(lit.)
- storage temp.
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- form
- powder
- InChI
- 1S/2C10H12ClN5O4.H2O/c2*11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9;/h2*2-3,5-6,9,17-19H,1H2,(H2,12,14,15);1H2/t2*3-,5-,6-,9-;/m11./s1
- InChIKey
- WRURCFOLSGPTMO-IZGCVNAISA-N
- SMILES
- O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC(Cl)=N3)O[C@@H]1CO.O[C@H]4[C@@H](O)[C@H](N(C=N5)C6=C5C(N)=NC(Cl)=N6)O[C@@H]4CO.O
- CAS DataBase Reference
- 81012 · 81012-94-4
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H332-H335
- Precautionary statements
- 261 · P261-P280-P305+P351+P338
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xn
- Risk Statements
- 22 · 22
- Safety Statements
- 36 · 36
- WGK Germany
- 3 · 3
- Hazard Note
- Harmful
- HS Code
- 2934999090 · 2934999090
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 Oral · Acute Tox. 4 Oral
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- hs_code
- 2934999090
- risk_code
- 22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- hazard_note
- Harmful
- safety_code
- 36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H332-H335
- Hazard Classifications
- Acute Tox. 4 Oral
- Precautionary statements
- P261-P280-P305+P351+P338
Chemistry & industry
Applications
Uses2-Chloroadenosine can effectively inhibit the expression of tumor metastasis-related genes mtal and mRNA, and has inhibitory effects on various cancer cells. For example, it inhibits the in vitro invasion of highly metastatic human ovarian cancer cells HO-8910PM and the growth of human prostate cancer cells. 2-Chloroadenosine can also significantly increase spinal cord blood flow after injury, thereby improving post-injury neurological function. Furthermore, it is an important pharmaceutical intermediate; it can be used as a raw material to synthesize the anti-leukemia drug cladribine (2-chlorodeoxyadenosine).
Suppliers55 total
北京华美互利生物化工010-56205725 · [email protected]
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Hangzhou Pharma & Chem Co., Ltd.+86-0571-87040515 +8613958180668 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
郑州鸿晟医药科技有限公司0371-55695890 15637198702 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
上海晶抗生物工程有限公司021-54721350 13524668266 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
南京红杉生物科技有限公司158-05183379 15805183379 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
成都麦卡希化工有限公司028-85632863 18108198598 · [email protected]
越林试剂021-62960152 · [email protected]
南京德尔诺医药科技有限公司02585057128;025-86957866 13952093866 · [email protected]
上海毕得医药科技股份有限公司400-164-7117 18317119277 · [email protected]
上海卓因生物科技有限公司021-61317773 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
杭州六可生物科技有限公司+86-571-86912261 19975279805 · [email protected]
南兴化工（江苏）有限公司0512-66387035 18662433356 · [email protected]
芜湖诺威化学技术有限公司0553-8233716 18055326116 · [email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
武汉福鑫化工有限公司+86-2759207851; +86-18007136271 · [email protected]
康幸生物科技（上海）有限公司021-61556450 15800904410
Shanghai Acmec Biochemical Technology Co., Ltd.+86-18621343501 · [email protected]
江苏艾康生物医药研发有限公司025-58859352 13913916777 · [email protected]
武汉赢元贝商贸有限公司86-13349903920 13349903920 · [email protected]
上海吉至生化科技有限公司021-4009004166/18616739031 18616739031 · [email protected]
career henan chemical co+86-0371-86658258 · [email protected]
海蔚化学86-21-51086038 · [email protected]
上海蓝乐鸟实业有限公司15021845385 · [email protected]
Aladdin Scientific[email protected]
嘉兴瑞恒生物科技有限公司0573-0573-82672231 13757365595 · [email protected]
爆牛贸易重庆有限公司+86-023-6139-8061 +86-86-13650506873 · [email protected]
上海亿万化工有限公司00-18662433356 18662433356 · [email protected]
SHANGHAI KEAN TECHNOLOGY CO., LTD.+8613817748580 · [email protected]
Hebei Fengmu Trading Co., Ltd.+86-15632192160 · [email protected]
上海捷世凯生物科技有限公司021-57520305 13795461237 · [email protected]
重庆卡兰医药有限公司[email protected]
广东翁江化学试剂有限公司0751-2815983 13927872582 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
陕西西化化学工业有限公司18161915376 · [email protected]
Hefei TNJ Chemical Industry Co.,Ltd.+86-0551-65418684 +86-18949823763 · [email protected]
Related reactions
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Compound notes
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