CAS 7699-31-2 1,2-Diethylhydrazine dihydrochloride (HCID 24372)

Overview

1,2-diethylhydrazine dihydrochloride is a white powder. (NTP, 1992)

Names & identifiers

Preferred name: 1,2-Diethylhydrazine dihydrochloride
IUPAC: 1,2-diethylhydrazine;dihydrochloride
English name: N,N'-Diethylhydrazine dihydrochloride
Molecular formula: C4H14Cl2N2
Molecular weight: 161.07

Names & synonyms

1,2-Diethylhydrazine dihydrochloride7699-31-2N,N'-Diethylhydrazine dihydrochlorideCCRIS 8919UNII-X3O3IWE4TGX3O3IWE4TGHydrazine, 1,2-diethyl-, dihydrochlorideDTXSID2025056RefChem:71879DTXCID405056N,N'Diethylhydrazine dihydrochlorideHydrazine, 1,2diethyl, dihydrochloride

Show more names

1,2-Diethylhydrazine2HCl-Diethylhydrazine dihydrochloride1,2-diethyl-hydrazindihydrochlorideHydrazine, 1,2-diethyl, dihydrochloride.N,Nzzhlxy-Diethylhydrazine dihydrochlorideN,N''-DIETHYLHYDRAZINE DIHYDROCHLORIDE: TECH., 90%N,N'-DIETHYLHYDRAZINE DIHYDROCHLORIDE ISO 9001：2015 REACH

624-628-51,2-diethylhydrazine;dihydrochlorideMFCD00012523N,N-Diethylhydrazine dihydrochlorideN',N'-Diethylhydrazine Dihydrochloridediethylhydrazine dihydrochlorideSCHEMBL3118416CHEMBL1203769

Database identifiers

CAS: 7699-31-2
PubChem CID: 24372
DTXSID: DTXSID2025056
ChEMBL: CHEMBL1203769
UNII: X3O3IWE4TG
EC Number: 624-628-5

Properties

Computed structural properties

Topological polar surface area: 24.1 Å²
Hydrogen bond donors: 4
Hydrogen bond acceptors: 2
Rotatable bonds: 3
Heavy atoms: 8
Formal charge: 0
Complexity: 17.5

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Hydrazines

Solubilitygreater than or equal to 100 mg/mL at 64 °F (NTP, 1992)

Melting Point336 °F (decomposes) (NTP, 1992)

Physical Description · 2 items

1,2-diethylhydrazine dihydrochloride is a white powder. (NTP, 1992)

White solid; [CAMEO] White odorless crystalline powder; [Alfa Aesar MSDS]

Physicochemical properties

Melting point: 169 °C · 169 °C (dec.)(lit.)
storage temp.: Room Temperature
solubility: DMSO, Methanol
form: Solid
color: Off-White
BRN: 3668380 · 3668380
InChI: 1S/C4H12N2.2ClH/c1-3-5-6-4-2;;/h5-6H,3-4H2,1-2H3;2*1H
InChIKey: NMTDWUVFGOBBAX-UHFFFAOYSA-N
SMILES: Cl[H].Cl[H].CCNNCC
CAS DataBase Reference: 7699 · 7699-31-2
FDA UNII: 3 O3IWE4TG · X3O3IWE4TG
EPA Substance Registry System: 1 · 1,2-Diethylhydrazine dihydrochloride (7699-31-2)
UNSPSC Code: 12352100 · 12352100
NACRES: 22 · NA.22
Symbol(GHS): 7 · GHS07,GHS08
Signal word: Danger
Hazard statements: 302 · H302+H312+H332-H315-H319-H335-H350
Precautionary statements: 280 · P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313
target organs: Respiratory system
PPE: 2 · Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes: T
Risk Statements: 45 · 45-20/21/22-36/37/38
Safety Statements: 53 · 53-26-36/37/39-45
RIDADR: 2811 · 2811
WGK Germany: 3 · 3
RTECS: 2295000 · MV2295000
PackingGroup: III
Storage Class: 6.1 C · 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
Hazard Classifications: 4 DermalAcute · Acute Tox. 4 DermalAcute Tox. 4 InhalationAcute Tox. 4 OralCarc. 1BEye Irrit. 2Skin Irrit. 2STOT SE 3

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P203, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 43 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

DOT LabelPoison

Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include a burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting.

Hazards Summary · 1 item

A strong reducing agent; [CAMEO] A severe irritant that may cause corrosive injuries at high concentrations; Harmful by ingestion, inhalation, and skin absorption; [NTP] A skin and strong eye irritant; Toxic by ingestion and skin absorption; [Alfa Aesar MSDS]

Reactive GroupAzo, Diazo, Azido, Hydrazine, and Azide Compounds

Reactivity AlertsStrong Reducing Agent

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

Toxicology

Adverse EffectsDermatotoxin - Skin burns.

Safety data

PPE: Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
wgk: 3
rtecs: MV2295000
ridadr: 2811
risk_code: 45-20/21/22-36/37/38
Signal word: Danger
Symbol(GHS): GHS07,GHS08
hazard_code: T
safety_code: 53-26-36/37/39-45
Storage Class: 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
packing_group: III
target organs: Respiratory system
Hazard statements: H302+H312+H332-H315-H319-H335-H350
Hazard Classifications: Acute Tox. 4 DermalAcute Tox. 4 InhalationAcute Tox. 4 OralCarc. 1BEye Irrit. 2Skin Irrit. 2STOT SE 3
Precautionary statements: P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313

Chemistry & industry

Applications · 3 items

UsesReactant involved in:• ;Bromopyridazinedione-mediated protein and peptide bioconjugation1• ;Synthesis of human neutrophil proteinase 3 inhibitors2• ;Three-component cascade processes for sythesis of aminoisoindolones and phthalazones3• ;Stereoselective heterocyclization for synthesis of substituted hexahydropyrazolodiazepinecarboxylates4• ;Synthesis of azacycloalkanes, isoindoles, pyrazole, pyrazolidine, and phthalazine derivatives5

UsesReactant involved in:Bromopyridazinedione-mediated protein and peptide bioconjugationSynthesis of human neutrophil proteinase 3 inhibitorsThree-component cascade processes for sythesis of aminoisoindolones and phthalazonesStereoselective heterocyclization for synthesis of substituted hexahydropyrazolodiazepinecarboxylatesSynthesis of azacycloalkanes, isoindoles, pyrazole, pyrazolidine, and phthalazine derivatives

General DescriptionWhite powder.