HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.8.0
  1. Home
  2. /Compound

Ammonium arsenate

HCID 24574
New noteNew reactionRequest quotes
Print preview
Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
Substructure searchFind similar structures

Basic information

CAS
7784-44-3
Standard SMILES
O=[As]([O-])([O-])O.[NH4+].[NH4+]
InChIKey
XPVHUBFHKQQSDA-UHFFFAOYSA-N
Molecular formula
(NH4)2HAsO4
Average molar mass
176 g/mol
Monoisotopic mass
175.977826

Overview

Ammonium arsenate appears as a white crystalline solid. Toxic by ingestion.

Names & identifiers

Preferred name
Ammonium arsenate
IUPAC
diazanium;hydrogen arsorate
English name
AMMONIUM ARSENATE
Molecular formula
AsH6NO4
Molecular weight
158.97

Names & synonyms

AMMONIUM ARSENATEAmmonium acid arsenate7784-44-3Diammonium hydrogenarsenateDibasic ammonium arsenateDIAMMONIUM ARSENATESecondary ammonium arsenateDiammonium hydrogen arsenateDiammonium monohydrogen arsenateUN1546Arsenic acid (H3AsO4), diammonium saltdiammonium hydrogen arsorate
Show more names
hydrogen arsorateammoniumacidarsenateAMMONIUM ARSENATE (DI)dibasicammoniumarsenatesecondaryammoniumarsenateAMMONIUM ARSENATE (ORTHO)Ammonium hydrogenarsenateAMMONIUM ARSENATE TRIBASIC
AMMONIUM ARSENATE, (SOLID)AMMONIUM ARSENATE, [SOLID]Ammonium arsenic acidRefChem:557658(NH4)3AsO4AMMONIUM ARSENATE ((NH4)2ASHO4)AMMONIUM ARSENATE ((NH4)2HASO4)diazanium;hydrogen arsorate

Database identifiers

CAS
7784-44-3
PubChem CID
24574
DTXSID
DTXSID0036895
EC Number
232-067-9

Properties

Computed structural properties

Topological polar surface area
85.4 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
4
Rotatable bonds
0
Heavy atoms
7
Formal charge
0
Complexity
46.5

Experimental & physicochemical properties

Chemical Classes · 2 items

Metals -> Arsenic Compounds, Inorganic

Carcinogens

Density2.0 g/cm³
SolubilitySolubility in water: good
Physical Description · 3 items

Ammonium arsenate appears as a white crystalline solid. Toxic by ingestion.

White solid, soluble in water; Decomposes in hot water; [Hawley]

COLOURLESS CRYSTALS WITH CHARACTERISTIC ODOUR.

Physicochemical properties

Melting point
10 · decomposes [CRC10]
Density
1.99 · 1.990
solubility
2 O · soluble in H2O
form
powder
color
white
Water Solubility
2 O, · soluble H2O, decomposed by hot H2O [HAW93]
REACH Annex XVII Substances List
Diammonium hydrogenarsenate (7784-44-3)

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Hazard information

Regulatory Information · 2 items

Restricted substance: Diammonium hydrogenarsenate

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelPoison
Fire Hazards · 3 items

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.

Health Hazards · 2 items

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

· Highly toxic, may be fatal if inhaled, ingested or absorbed through skin.

Hazards SummaryA skin, eye, and respiratory tract irritant; May cause arsenic poisoning; [ICSC] Toxic by ingestion; [MSDSonline] See Arsenic and the linked occupational diseases.
DOT ID and Guide1546 151
Reactive GroupSalts, Acidic
EC ClassificationSymbol: T, N; R: 45-23/25-50/53; S: 53-45-60-61; Note: A, E
UN ClassificationUN Hazard Class: 6.1; UN Pack Group: II
Reactivity ProfileSolutions of AMMONIUM ARSENATE are acidic. They neutralize bases in reactions that generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acids.

Chemistry & industry

Pharmacology

Metabolism/Metabolites · 1 item

Arsenic is absorbed mainly by inhalation or ingestion, as to a lesser extent, dermal exposure. It is then distributed throughout the body, where it is reduced into arsenite if necessary, then methylated into monomethylarsenic (MMA) and dimethylarsenic acid (DMA) by arsenite methyltransferase. Arsenic and its metabolites are primarily excreted in the urine. Arsenic is known to induce the metal-binding protein metallothionein, which decreases the toxic effects of arsenic and other metals by binding them and making them biologically inactive, as well as acting as an antioxidant. (L20)

Uses & manufacturing

UsesIt is used as herbicide, insecticide,and rodenticide (L926).

Applications

General DescriptionA white crystalline solid. Toxic by ingestion.

Related reactions

0 records
New reaction record

No reaction records under the current filter.

Compound notes

Loading…

On this pageBasic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
More actions
New noteNew reactionRequest quotes
EPA Substance Registry System
Arsenic acid (H3AsO4), diammonium salt (7784-44-3)
RIDADR
1546 · UN 1546
HazardClass
6.1 · 6.1
PackingGroup
II
HS Code
28429090 · 28429090
Chemical Dangers · 1 item

Decomposes on heating. This produces toxic and corrosive fumes. Reacts with acids. This produces toxic arsine gas (see ICSC 0222). Attacks many metals such as iron, aluminium and zinc in the presence of water. This produces toxic fumes of arsenic (see ICSC 0013) and arsine (see ICSC 0222). Reacts with strong oxidants and bases. This produces toxic and corrosive fumes including ammonia.

Packaging and LabellingDo not transport with food and feedstuffs.

Safety & protection

Fire Fighting · 2 items

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

In case of fire in the surroundings, use appropriate extinguishing media.

First Aid Measures · 4 items

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Seek medical attention if you feel unwell.

Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.

Rinse mouth. Refer immediately for medical attention.

Accidental Release Measures · 2 items

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

First Aid · 2 items

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

General First Aid:

Safe Storage · 1 item

Provision to contain effluent from fire extinguishing. Separated from acids, strong oxidants, bases and food and feedstuffs. Well closed. Dry. Do NOT store or transport in containers made from metal. Store in an area without drain or sewer access.

Exposure Control and Personal Protection · 2 items

· Wear positive pressure self-contained breathing apparatus (SCBA).

Biological Exposure Indices (BEI) [ACGIH] - Inorganic arsenic plus methylated metabolites in urine = 35 ug As/L; end of workweek;

Nonfire Spill ResponseExcerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:
Spillage Disposal · 1 item

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Vacuum with specialist equipment or carefully sweep into containers. Carefully collect remainder. Then store and dispose of according to local regulations.

Isolation and Evacuation · 2 items

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

Immediate precautionary measure

Eye PreventionWear face shield or eye protection in combination with breathing protection if powder.
Inhalation RiskA harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
Skin PreventionProtective gloves. Protective clothing.

Toxicology

Treatment · 1 item

Arsenic poisoning can be treated by chelation therapy, using chelating agents such as dimercaprol, EDTA or DMSA. Charcoal tablets may also be used for less severe cases. In addition, maintaining a diet high in sulfur helps eliminate arsenic from the body. (L20)

Health EffectsArsenic poisoning can lead to death from multi-system organ failure, probably from necrotic cell death, not apoptosis. Arsenic is also a known carcinogen, esepcially in skin, liver, bladder and lung cancers. (T1, L20)
Adverse EffectsNeurotoxin - Sensorimotor
Exposure Routes · 2 items

The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Oral (L2) ; inhalation (L2); dermal (L2)

Toxicity Summary · 1 item

Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by competing with phosphate it uncouples oxidative phosphorylation, thus inhibiting energy-linked reduction of NAD+, mitochondrial respiration, and ATP synthesis. Hydrogen peroxide production is also increased, which might form reactive oxygen species and oxidative stress. Arsenic's carginogenicity is influenced by the arsenical binding of tubulin, which results in aneuploidy, polyploidy and mitotic arrests. The binding of other arsenic protein targets may also cause altered DNA repair enzyme activity, altered DNA methylation patterns and cell proliferation. (T1, A17)

Signs and Symptoms · 4 items

Cough. Sore throat.

Redness. Pain.

Abdominal pain. Diarrhoea. Vomiting. Burning sensation in the throat and chest. Headache. Weakness. Shock or collapse.

Exposure to lower levels of arsenic can cause nausea and vomiting, decreased production of red and white blood cells, abnormal heart rhythm, damage to blood vessels, and a sensation of burn (T1).

ICSC Environmental DataThe substance is toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be taken to avoid any additional release, for example through inappropriate disposal.
Carcinogen Classification1, carcinogenic to humans. (L135)

Safety data

ridadr
UN 1546
hs_code
28429090
hazard_class
6.1
packing_group
II