Basic information
- CAS
7791-13-1- Standard SMILES
O.O.O.O.O.O.[Cl-].[Cl-].[Co+2]- InChIKey
GFHNAMRJFCEERV-UHFFFAOYSA-L- Molecular formula
- Cl2Co.6H2O
- Average molar mass
- 237.93 g/mol
- Monoisotopic mass
- 236.934287
Overview
Cobalt chloride hexahydrate is a hydrate of cobalt chloride containing cobalt (in +2 oxidation state), chloride and water moieties in the ratio 1:2:6. It has a role as an allergen. It contains a cobalt dichloride.
Names & identifiers
- Preferred name
- Cobaltous chloride hexahydrate
- IUPAC
- cobalt(2+);dichloride;hexahydrate
- English name
- Cobalt chloride hexahydrate
- Molecular formula
- Cl2CoH2O
- Molecular weight
- 147.85
Names & synonyms
Cobalt chloride hexahydrateCobalt(II) chloride hexahydrateCobalt dichloride hexahydrateChlorek cobaltawyCobalt chloride, hexahydratecobalt chloride hydrateCobaltous chloride, hexahydrateCobaltous chloride hexahydratecobalt (II) chloride hexahydrateChlorek cobaltawy [Polish]17AVG63ZBCCobalt chloride (CoCl2), hexahydrate
Show more names
COClCOBALTOUS CHLORIDEchlorekcobaltawyCobalt chlordieCobaltousChlorideArCOBALT CHLORIDE XTLCOBALT CHLORIDE, ACS
CCRIS 7729COBALT(II) CHLORIDE, HEXAHYDRATECHEBI:53503cobalt(2+) dichloride hexahydrateCobalt(II) chloride--water (1/7)COBALTOUS CHLORIDE HEXAHYDRATE [MI]COBALT CHLORIDE HEXAHYDRATE [WHO-DD]RefChem:578229
Database identifiers
- CAS
7791-13-1- PubChem CID
- 24643
Properties
Computed structural properties
- Topological polar surface area
- 6 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 0
- Heavy atoms
- 9
- Formal charge
- 0
- Complexity
- 0
Experimental & physicochemical properties
Density1.924 @25 °C
Boiling Point1049 °C @760 [mm Hg]
Melting Point86 °C
Physical DescriptionLiquid
Physicochemical properties
- Melting point
- 86 °C · 86 °C
- Boiling point
- 1049 °C · 1049 °C
- Density
- 3.35 · 3.35
- bulk density
- 1250 kg/m3 · 1250kg/m3
- vapor pressure
- 40 mm · 40 mm Hg ( 0 °C)
- storage temp.
- 5 °C · Store at +5°C to +30°C.
- solubility
- 191 g/l · 191g/l
- form
- Solid
- color
- Red-purple
- Specific Gravity
- 1.924 · 1.924
- PH
- 4.9 · 4.9 (50g/l, H2O, 25℃)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302+H332 (17.5%): Harmful if swallowed or if inhaled [Warning Acute toxicity, oral; acute toxicity, inhalation]
P203, P233, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P318, P321, P330, P333+P317, P342+P316, P362+P364, P391, P403, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 126 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H302: Harmful if swallowed [Warning Acute toxicity, oral]
Hazard information
Regulatory Information
Chemical: Cobalt(II) chloride, hexahydrate
Directive (EC) No 46/2002
Cobalt chloride (CoCl2), hexahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Cobalt chloride (CoCl2), hexahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Cobalt (II) chloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationPEC / SN / Other assessments - Common skin sensitisersâhazard classification: Health
Hazard Classes and Categories
Acute Tox. 4 (99.2%)
Acute toxicity - category 4
Safety & protection
Protective Action Criteria (PAC)
Chemistry & industry
Uses & manufacturing
U.S. Production2023: 50,000 - <250,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesNot Known or Reasonably Ascertainable
General Manufacturing InformationAgriculture, Forestry, Fishing and Hunting
Applications
UsesCobalt(II) chloride has several applications. It is used in hygrometers; as a humidity indicator; as a temperature indicator in grinding; as a foam stabilizer in beer; in invisible ink; for painting on glass; in electroplating; and a catalyst in Grignard reactions, promoting coupling with an organic halide. It also is used to prepare several other cobalt salts; and in the manufacture of synthetic vitamin B12.
UsesCobalt(II) chloride hexahydrate (CoCl2·6H2O) has been found to be an efficient catalyst for the one-pot synthesis of biscoumarin derivatives through a combination of aromatic aldehydes and 4-hydroxycoumarin in aqueous media at 70°C. Cobalt chloride hexahydrate can be used as an inducer of HIF-1 production used to study apoptotic effects in HepG2 cells. It is also used as APHA color standard.
General DescriptionCobalt(II) chloride hexahydrate has a cobalt ion surrounded by a tetragonal arrangement of chloride ligands. Four water molecules occupy a square plane about cobalt while chloride ions occupy axial positions. Its crystals belong to the monoclinic lattice system.
Preparation methods
PreparationCobalt(II) chloride is prepared by the action of cobalt metal or its oxide, hydroxide, or carbonate with hydrochloric acid: Co(OH)2 + 2HCl → CoCl2 + 2H2O The solution on concentration and cooling forms crystals of hexahydrate which on heating with SOCl2 dehydrates to anhydrous cobalt(II) chloride. Alternatively, the hexahydrate may be converted to anhydrous CoCl2 by dehydration in a stream of hydrogen chloride and dried in vacuum at 100–150°C. The anhydrous compound also may be obtained by passing chlorine over cobalt powder.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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