Basic information
- CAS
7791-20-0- Standard SMILES
O.O.O.O.O.O.[Cl-].[Cl-].[Ni+2]- InChIKey
LAIZPRYFQUWUBN-UHFFFAOYSA-L- Molecular formula
- Cl2Ni.6H2O
- Average molar mass
- 237.69 g/mol
- Monoisotopic mass
- 235.936435
Overview
Nickel chloride hexahydrate is a hydrate of nickel chloride containing nickel (in the +2 oxidation state), chloride and water moeities in the ratio 1:2:6. It has a role as a sensitiser. It contains a nickel dichloride.
Names & identifiers
- Preferred name
- Nickel chloride hexahydrate
- IUPAC
- nickel(2+);dichloride;hexahydrate
- English name
- Nickel(II) chloride hexahydrate
- Molecular formula
- Cl2Ni.6H2O
- Molecular weight
- 237.69
Names & synonyms
Nickel dichloride hexahydrateNickel chloride (NiCl2), hexahydrateNickel(II) chloride, hexahydrateT8365BUD85CHEBI:53542RefChem:853859DTXCID5021170616-576-77791-20-0DTXSID7041170Nickel chloride hexahydrateNickel(II) chloride hexahydrate
Show more names
NiCl2.6H2ONICKEL CHLORIDE, HEXAHYDRATE 99.998%Nickel(II)chloride,hexahydrate(1:2:6)(II) chLNickel chloridNickelChlorideAroride hexahydrateNichelous ChlorideNICKELOUS CHLORIDECOULOMETRY REAGENT
Nickelous chloride hexahydrateCl2NiO6nickelous;dichloride;hexahydratenickel chloride--water (1/6)nickel(2+);dichloride;hexahydrateNICKEL(2+) CHLORIDE HEXAHYDRATENICKEL CHLORIDE HEXAHYDRATE (OUS)SCHEMBL117189
Database identifiers
- CAS
7791-20-0- PubChem CID
- 24645
- ChEBI
CHEBI:53542- UNII
- T8365BUD85
- EC Number
- 616-576-7
Properties
Computed structural properties
- Topological polar surface area
- 6 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 0
- Heavy atoms
- 9
- Formal charge
- 0
- Complexity
- 0
Experimental & physicochemical properties
Chemical Classes
Metals -> Nickel Compounds, Inorganic
Carcinogens
Density3.55 @25 °C
Boiling Point987 °C @760 [mm Hg]
Vapor Pressure1 [mm Hg] @671 °C
Physical Description
Liquid; Liquid; Other Solid; CBI
Green deliquescent crystals or powder; [Merck Index] Available as a solid or concentrated solution; [Ullmann]
Physicochemical properties
- Melting point
- 140 °C · 140 °C (anhydrous substance; decomposes)
- Density
- 1.92 g/cm · 1.92 g/cm 3 (anhydrous substance)
- bulk density
- 640 kg/m3 · 640kg/m3
- Flash point
- Not applicable
- storage temp.
- 30 °C · Store below +30°C.
- solubility
- 2540 g/l · 2540g/l
- form
- powder to crystal
- color
- White to Green to Dark green to Dark blue; Light yellow
- PH
- 4.9 · 4.9 (100g/l, H2O, 20℃)
- Water Solubility
- 2540 G/L · 2540 G/L (20 ºC)
- Sensitive
- Hygroscopic
- Merck
- 14 · 14,6505
- Exposure limits
- 0.1 mg/m3NIOSH: · ACGIH: TWA 0.1 mg/m3NIOSH: IDLH 10 mg/m3; TWA 0.015 mg/m3
- Stability
- Stable. Hygroscopic. Incompatible with peroxides.
- Major Application
- battery precursorscatalystsmaterial synthesis precursor
- Cosmetics Ingredients Functions
- pH ADJUSTERS
- InChI
- 1S/2ClH.Ni.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2
- InChIKey
- LAIZPRYFQUWUBN-UHFFFAOYSA-L
- SMILES
- [H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].[H]O[H].Cl[Ni]Cl
- CAS DataBase Reference
- 7791 · 7791-20-0(CAS DataBase Reference)
- FDA UNII
- 8365 BUD85 · T8365BUD85
- EPA Substance Registry System
- Nickel chloride (NiCl2), hexahydrate (7791-20-0)
- UNSPSC Code
- 12352302 · 12352302
- NACRES
- 71 · NA.71
- Symbol(GHS)
- 6 · GHS06,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- 301 · H301+H331-H315-H317-H334-H341-H350i-H360D-H372-H410
- Precautionary statements
- 202 · P202-P273-P280-P301+P310-P302+P352-P304+P340+P311
- target organs
- Lungs
- PPE
- 3 · Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- Hazard Codes
- T,N,Xi
- Risk Statements
- 45 · 45-25-36/38-43-50/53-68-48/23-42/43-38-23/25-61-49
- Safety Statements
- 53 · 53-36/37-45-60-61-37-29-24
- RIDADR
- 3288 · UN 3288 6.1/PG 3
- WGK Germany
- 3 · 3
- RTECS
- 6480000 · QR6480000
- TSCA
- Yes
- HazardClass
- 6.1 · 6.1
- PackingGroup
- III
- HS Code
- 28273500 · 28273500
- Storage Class
- 6.1 C · 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- Hazard Classifications
- 3 InhalationAcute · Acute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1Carc. 1A InhalationMuta. 2Repr. 1BResp. Sens. 1Skin Irrit. 2Skin Sens. 1STOT RE 1 Inhalation
- Toxicity
- 50 orally · LD50 orally in Rabbit: 186 mg/kg
- Limited Quantities
- 5 L · 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301+H331 (16%): Toxic if swallowed or if inhaled [Danger Acute toxicity, oral; acute toxicity, inhalation]
P203, P233, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P318, P319, P321, P330, P332+P317, P333+P317, P342+P316, P362+P364, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 237 reports by companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H301: Toxic if swallowed [Danger Acute toxicity, oral]
Hazard information
Regulatory Information
Chemical: Nickel chloride (NiCl2), hexahydrate
Nickel chloride (NiCl2), hexahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Nickel chloride (NiCl2), hexahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Nickel (II) chloride, hexahydrate: Does not have an individual approval but may be used under an appropriate group standard
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Other Safety InformationIMAP assessments - Nickel chloride: Human health tier II assessment
Hazards SummaryMay cause sensitization of skin and respiratory tract; [MSDSonline] SeeNickel and linked occupational diseases.
Hazard Classes and Categories
Acute Tox. 3 (100%)
Carcinogenicity - category 1A
Acute toxicity (Oral) - Category 3
Carcinogens
Safety & protection
Threshold Limit Values (TLV)0.1 [mg/m3], inhalable fraction, as Ni
Permissible Exposure Limit (PEL)1.0 [mg/m3], as Ni
Protective Action Criteria (PAC)
1.2 [mg/m3]
3.5 [mg/m3]
21 [mg/m3]
Immediately Dangerous to Life or Health (IDLH)10.0 [mg/m3], as Ni
Toxicology
Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 3
- tsca
- Yes
- rtecs
- QR6480000
- ridadr
- UN 3288 6.1/PG 3
- hs_code
- 28273500
- Toxicity
- LD50 orally in Rabbit: 186 mg/kg
- risk_code
- 45-25-36/38-43-50/53-68-48/23-42/43-38-23/25-61-49
- Signal word
- Danger
- Symbol(GHS)
- GHS06,GHS08,GHS09
- hazard_code
- T,N,Xi
- safety_code
- 53-36/37-45-60-61-37-29-24
- hazard_class
- 6.1
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- packing_group
- III
- target organs
- Lungs
- Hazard statements
- H301+H331-H315-H317-H334-H341-H350i-H360D-H372-H410
- Limited Quantities
- 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
- Hazard Classifications
- Acute Tox. 3 InhalationAcute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1Carc. 1A InhalationMuta. 2Repr. 1BResp. Sens. 1Skin Irrit. 2Skin Sens. 1STOT RE 1 Inhalation
- Precautionary statements
- P202-P273-P280-P301+P310-P302+P352-P304+P340+P311
Chemistry & industry
Uses & manufacturing
Uses
Used in electroplating and to make nickel catalysts; [Merck Index]
Electroplating [Category: Plate]
U.S. Production2023: 400,000 - <550,000 lb
Consumer UsesProcessing aids, specific to petroleum production
Industry UsesPlating agent
General Manufacturing InformationAll Other Chemical Product and Preparation Manufacturing
Applications
UsesNickel(II) chloride hexahydrate has been used:in the preparation of nickel platting solution for galvanostatically coating nickel inside the reduced carbon layer during the synthesis of multiwall carbon nanotube micromotorsin screening of metals for inflammatory effect on vascular endothelial cellsas an additive in artificial cerebrospinal fluid (ACSF) to analyse excitatory post synaptic currents (EPSPs) in the hippocampus slices
UsesNickel(II) chloride hexahydrate may be employed as a catalyst in the high yield synthesis of tetra-substituted pyrrole derivatives. It may be used for the conversion of tetrahydropyranyl (THP) and tert-butyldimethylsilyl (TBS) ethers to the corresponding hydroxyl compounds.
UsesAnhydr salt as absorbent for NH3 in gas masks. Hexahydrate for nickel electroplating; manufacture of nickel catalysts.
General DescriptionNickel(II) chloride hexahydrate is a nickel salt that can be used as a catalyst. It is cost effective and can be used in a variety of industrial processes. It can also be used in cross-coupling reactions.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
韶远科技（上海）有限公司4000665055 · [email protected]
山东信恒化工有限公司15269160602 15269160602 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
上海晶抗生物工程有限公司021-54721350 13524668266 · [email protected]
大连美仑生物技术有限公司0411-62910999 13889544652 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海景颜化工科技有限公司13817811078 · [email protected]
Additional notes
DefinitionChEBI: A hydrate of nickel chloride containing nickel (in the +2 oxidation state), chloride and water moeities in the ratio 1:2:6.
Related reactions
1 records
Compound notes
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