HomeMCPWorkbenchSkills
HomeWorkbenchNotificationsMe
Huagongshe Open Program：[email protected]AI access: llms.txt · MCP GuidePrivacy Policy · Terms of Service · Supportv1.7.8
  1. Home
  2. /Compound

Metasystox

HCID 24692
NotesReactions
Basic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes
Substructure searchFind similar structures

Basic information

CAS
12767-20-3
Standard SMILES
CCSCCOP(=S)(OC)OC.CCSCCSP(=O)(OC)OC
InChIKey
KPNPDRFFWQBXGT-UHFFFAOYSA-N
Molecular formula
C12H30O6P2S4
Average molar mass
460.6 g/mol
Monoisotopic mass
460.04004736

Overview

Methyl demeton is an oily colorless to pale yellow liquid with an unpleasant odor. Slightly water soluble.

Names & identifiers

Preferred name
Metasystox
IUPAC
1-dimethoxyphosphorylsulfanyl-2-ethylsulfanylethane;2-ethylsulfanylethoxy-dimethoxy-sulfanylidene-λ5-phosphane
English name
Demeton methyl powder(content>10%)
Molecular formula
2C6H15O3PS2
Molecular weight
460.575

Names & synonyms

Methyl demetonDemeton-methylDemeton methylMethyl systoxMetasystox forteDemeton MMethyl-mercaptophosMethylmerkaptofosMethyl demeton 25 EC8022-00-2Bayer 21/116B9PMD9I0FE
Show more names
Methyl 1059 powderDanazol Impurity 7Demetonmethylpowder(contenDemeton methyl powder(contentDemeton methyl powder(content>Demeton methyl powder(content>10%)Dimethylethylmercapto ethylthiophosphateOXYDEMETON-METHYL=S-(2(ETHYL-SULPHINYL)-ETHYL)O,O-DIMETHY.O,O-dimethyl-O-(2-(ethylthio)ethyl) thiophosphate mixed with-O,O-dimethyl-S-(2-(ethylthio)ethyl) thiophosphate
S(and O)-2-(Ethylthio)ethyl O,O-dimethyl phosphorothioatePhosphorothioic acid, O-(2-(ethylthio)ethyl) O,O-dimethyl ester, mixt. with S-(2-(ethylthio)ethyl) O,O-dimethyl esterPhosphorothioic acid, O-(2-(ethylthio)ethyl) O,O-dimethyl ester, mixt. with S-(2-(ethylthio)ethyl) O,O-dimethyl phosphorothioateMethylmercaptophosRefChem:157840DTXSID3040277BAYER-21/116Phosphorothioic acid, S-(2-(ethylthio)et hyl) O,O-dimethyl ester

Properties

Computed structural properties

Topological polar surface area
171 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
10
Rotatable bonds
14
Heavy atoms
24
Formal charge
0
Complexity
291

Experimental & physicochemical properties

PesticidesPesticides -> Organophosphate Insecticides
LogP1.32
Density · 4 items

1.2 at 68 °F (NTP, 1992) - Denser than water; will sink

Relative density (water = 1): 1.2

1.20

1.20

Solubility · 3 items

Slightly soluble (NTP, 1992)

Solubility in water, g/100ml at 20 °C: 2.2

0.03-0.3%

Boiling Point · 3 items

Decomposes (NIOSH, 2024)

decomposes

Decomposes

Vapor Pressure · 5 items

0.0004 mmHg (NIOSH, 2024)

0.0004 [mmHg]

Vapor pressure, Pa at 20 °C: 0.04

0.0004 mmHg

0.0004 mmHg

Physical Description · 5 items

Methyl demeton is an oily colorless to pale yellow liquid with an unpleasant odor. Slightly water soluble.

Oily, colorless to pale-yellow liquid with an unpleasant odor. [insecticide] [Note: Technical grade consists of 2 isomers: thiono & thiolo.]; [NIOSH]

COLOURLESS-TO-PALE YELLOW OILY LIQUID WITH CHARACTERISTIC ODOUR.

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 3 items

Danger

H300: Fatal if swallowed [Danger Acute toxicity, oral]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P272, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Hazard information

Regulatory InformationThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
DOT LabelPoison
Fire Hazards · 2 items

Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.

Health HazardsExcerpt from NIOSH Pocket Guide for Methyl demeton:
Hazards Summary · 1 item

It is less toxic than demeton. [ACGIH] A cholinesterase inhibitor that may cause CNS effects; Can be absorbed through skin; [ICSC] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]

Chemistry & industry

Pharmacology

MeSH Pharmacological ClassificationPesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.

Uses & manufacturing

Uses · 3 items

Used to kill insects on garden crops, fruit, and hops; [ACGIH]

Not registered for use in the US; [EPA PPIS]

Farming (Pesticides) [Category: Industry]

Applications · 4 items

DescriptionDemeton-methyl is a colorless to pale yellowoily liquid with an unpleasant odor. It is a mixture ofDemeton-S and Demeton-O and may be formulated in aflammable organic solvent that may alter the physical properties shown here. Molecular weight = 230.30. Specific gravity(H2O:1) 5 1.2; Boiling point = decomposes below 100℃.Hazard Identification (based on NFPA-704 M RatingSystem): Health 2, Flammability 2, Reactivity 0. Slightly soluble in water; solubility = 0.03-0.3% at 20℃.

UsesSystemic insecticide.

UsesDemeton Methyl is an organophosphorus pesticides.

General DescriptionOily colorless to pale yellow liquid with an unpleasant odor. Slightly water soluble.

Suppliers3 total

河北枫嘉新材料科技有限公司+86-0311-87836622 +86-18712993135 · [email protected]
爆牛贸易重庆有限公司+86-023-6139-8061 +86-86-13650506873 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.

Related reactions

0 records
New reaction record

No reaction records under the current filter.

Compound notes

Loading…

On this pageBasic informationOverviewNames & identifiersPropertiesSafety & regulationChemistry & industryRelated reactionsCompound notes

Database identifiers

CAS
12767-20-3、8022-00-2
PubChem CID
24692
DTXSID
DTXSID10925932

Oily, colorless to pale-yellow liquid with an unpleasant odor.

Oily, colorless to pale-yellow liquid with an unpleasant odor. [insecticide] [Note: Technical grade consists of 2 isomers: thiono & thiolo.]

Physicochemical properties

Density
1.19 · 1.1900
refractive index
1.5063 · 1.5063
Exposure limits
0.2 mg/m3 · PC-TWA: 0.2 mg/m3
FDA UNII
9 PMD9I0FE · B9PMD9I0FE
EPA Substance Registry System
Demeton-methyl (8022-00-2)
RIDADR
3018 · 3018
OEB
C
OEL
0.5 mg/m3 · TWA: 0.5 mg/m3 [skin]
HazardClass
6.1 · 6.1(a)
PackingGroup
II
Toxicity
50 in · LD50 in rats (mg/kg): 50-75 orally, 300-400 dermally (Edson)
Reactive Group
Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters
EC ClassificationSymbol: T, N; R: 24/25-51/53; S: (1/2)-28-36/37-45-61
UN ClassificationUN Hazard Class: 6.1; UN Pack Group: III
Reactivity Profile · 1 item

Organothiophosphates, such as METHYL DEMETON, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Chemical DangersDecomposes on burning. This produces phosphorous oxides and sulfur oxides.
Flammable LimitsCombustible Liquid
Packaging and LabellingDo not transport with food and feedstuffs.

Safety & protection

Fire Fighting · 2 items

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

Use water spray, powder, foam, carbon dioxide.

First Aid Measures · 4 items

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

First Aid · 2 items

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

(General first aid procedures)

Safe StorageKeep in a well-ventilated room. Separated from food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Exposure Control and Personal Protection · 2 items

Biological Exposure Indices (BEI) [ACGIH] - Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]

4.8 [mg/m3]

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Spillage Disposal · 1 item

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Isolation and EvacuationExcerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:
Eye PreventionWear face shield or eye protection in combination with breathing protection.
Fire PreventionNO open flames.
Inhalation RiskEvaporation at 20 °C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.
Skin PreventionProtective clothing. Protective gloves.

Toxicology

Target OrgansEyes, skin, respiratory system, central nervous system, cardiovascular system, blood cholinesterase
Adverse EffectsOther Poison - Organophosphate
Exposure Routes · 2 items

The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

inhalation, skin absorption, ingestion, skin and/or eye contact

Signs and Symptoms · 5 items

Convulsions. Dizziness. Laboured breathing. Nausea. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Unconsciousness.

MAY BE ABSORBED! See Inhalation.

Pupillary constriction. Blurred vision.

See Inhalation. Abdominal cramps. Diarrhoea. Vomiting.

irritation eyes, skin; ache eyes, rhinorrhea (discharge of thin nasal mucus); nausea, headache, dizziness, vomiting

ICSC Environmental DataThe substance is toxic to aquatic organisms. This substance may be hazardous to the environment. Special attention should be given to bees, mammals and birds. Avoid release to the environment in circumstances different to normal use.
Toxicity DataLCLo (cat) = 20 mg/m3/4hr

Safety data

OEB
C
OEL
TWA: 0.5 mg/m3 [skin]
ridadr
3018
Toxicity
LD50 in rats (mg/kg): 50-75 orally, 300-400 dermally (Edson)
hazard_class
6.1(a)
packing_group
II
+8618950047208 · [email protected]