Basic information
- CAS
9000-11-7- Standard SMILES
CC(=O)O.O=CC(O)C(O)C(O)C(O)CO- InChIKey
GZCGUPFRVQAUEE-UHFFFAOYSA-N- Molecular formula
- C8H16O8
- Average molar mass
- 240.21 g/mol
- Monoisotopic mass
- 240.08451746
Names & identifiers
- Preferred name
- Carmellose (JP17/NF/INN)
- IUPAC
- acetic acid;2,3,4,5,6-pentahydroxyhexanal
- English name
- Carboxymethyl cellulose
- Molecular formula
- C6H12O6
- Molecular weight
- 180.15588
Names & synonyms
Carmellose (JP17/NF/INN)RefChem:1081259acetic acid;2,3,4,5,6-pentahydroxyhexanalCM-CelluloseCroscarmellosum [Latin]Carmellosum [INN-Latin]Carmelosa [INN-Spanish]CMC-4LFCroscarmellosum [INN-Latin]Croscarmelosa [INN-Spanish]FEMA No. 2239Carmellose [INN]
Show more names
CMCCarboxymethyl cellulosecroscarmelloseCarmellose2,3,4,5,6-pentahydroxyhexanalkmtsCM CELLULOSEpentahydroxyhexanalCarboxyl Methyl Celluloseacetic acid,2,3,4,5,6-pentahydroxyhexanal
Intrasite gel (TN).CarboxymethylcelluloseAcetic acid, hydroxy-, cellulose etherCroscarmellose (INN)UNII-05JZI7B19X7HCarmellose (Y0001214)SCHEMBL177710
Database identifiers
- CAS
9000-11-7- PubChem CID
- 24748
Properties
Computed structural properties
- Topological polar surface area
- 156 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 5
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 169
Physicochemical properties
- Density
- 1.05 g/cm3 · 1.050 g/cm3(Temp: 15-18 °C)
- FEMA
- 2239 · 2239 | CARBOXYMETHYLCELLULOSE
- storage temp.
- 2 · 2-8°C
- solubility
- 1 M · Practically insoluble in anhydrous ethanol. It swells with water to form a suspension and becomes viscid in 1 M sodium hydroxide.
- form
- preswollen, microgranular
- color
- White to off-white
- Odor
- odorless
- Stability
- Stable. Combustible. Incompatible with strong oxidizing agents.
- Major Application
- pharmaceutical (small molecule)
- Cosmetics Ingredients Functions
- BINDINGGEL FORMINGVISCOSITY CONTROLLINGBULKING
- InChI
- InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2
- InChIKey
- GZCGUPFRVQAUEE-UHFFFAOYSA-N
- SMILES
- C(=O)C(O)C(O)C(O)C(O)CO
- LogP
- -3.17 · -3.17
- CAS DataBase Reference
- 9000 · 9000-11-7(CAS DataBase Reference)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 1
- tsca
- TSCA listed
- rtecs
- FJ5700000
- hs_code
- 3912310000
- Toxicity
- LD50 unreported in mammal (species unspecified): 13340mg/kg
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
UsesCMC can significantly increase the viscosity of the solution as thickener, dispersion, emulsification, suspension, protective colloid and so on when it is dissolved in water, and it is physiologically harmless, it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.
UsesPharmaceutic aid (suspending agent); pharmaceutic aid (tablet excipient); pharmaceutic aid (viscosity-increasing agent).
Usescarboxymethyl cellulose (cellulose gum) is a thickener. used in cosmetic formulations when a reactant is not required or desired. often used in bath preparations, beauty masks, hand creams, and shampoos. It is considered a non-comedogenic raw material.
UsesCarboxymethylcellulose(CMC) is a gum that is water-soluble cellulose ether manufactured by reacting sodium monochloroacetate with alkali cellulose to form sodium . It dissolves in hot or cold water and is fairly stable over a pH range of 5.0–10.0, but acidification below pH 5.0 will reduce the viscosity and stability except in a special acid-stable type of CMC. A variety of types are available which differ in viscosity and degree of substitution (the number of sodium groups per unit). It functions as a thickener, stabilizer, binder, film former, and suspending agent. It is used in a variety of foods to include dressings, ice cream, baked goods, puddings, and sauces. The usage range is from 0.05 to 0.5%. Also termed cellulose gum.
Preparation methods
PreparationSodium carboxymethyl cellulose is produced by treating wood pulp or cotton linters with alkali and monochloroacetic acid. It occurs as a white- or cream-colored powder or granules.
Upstream & downstream products
Downstream products
Suppliers100 total
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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