6-Methyl-5-nitropyridin-2-amine

HCID 247976

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Basic information

CAS: 22280-62-2
Standard SMILES: Cc1nc(N)ccc1[N+](=O)[O-]
InChIKey: BGMZTBKXOFFTBJ-UHFFFAOYSA-N
Molecular formula: C6H7N3O2
Average molar mass: 153.14 g/mol
Monoisotopic mass: 153.05382646

Names & identifiers

Preferred name: 6-Methyl-5-nitropyridin-2-amine
IUPAC: 6-methyl-5-nitropyridin-2-amine
English name: 2-Amino-6-methyl-5-nitropyridine
Molecular formula: C6H7N3O2
Molecular weight: 153.14

Names & synonyms

6-methyl-5-nitropyridin-2-amineRefChem:543937675-118-422280-62-22-Amino-6-methyl-5-nitropyridine6-Amino-3-nitro-2-picoline2-amino-5-nitro-6-methylpyridine6-amino-3-nitro-2-methylpyridine2-amino-5-nitro-6-picolineMFCD000535826-Methyl-5-nitro-2-pyridinamine6-amino-2-methyl-3-nitropyridine

Show more names

6-Amino-3-Nitro-2-Picolin2-Amino-5-nitro-6-methylpyridi6-Amino-3-nitro-2-picoline,98%6-Amino-3-nitro-2-picoline ,97%6-methyl-5-nitro-pyridin-2-amine

2-Pyridinamine, 6-methyl-5-nitro-AKOS002676259AC-5416PS-4395SY0162162-Amino-5-Nitro-6-Methyl pyridine6-methyl-5-nitro-2-pyridylamineNSC63855

Database identifiers

CAS: 22280-62-2
PubChem CID: 247976
DTXSID: DTXSID00289772
EC Number: 675-118-4
Nikkaji: J83.170K

Properties

Computed structural properties

XLogP: 0.7
Topological polar surface area: 84.7 Å²
Hydrogen bond donors: 1
Hydrogen bond acceptors: 4
Rotatable bonds: 0
Heavy atoms: 11
Formal charge: 0
Complexity: 156

Physicochemical properties

Melting point: 185 · 185-189 °C
Boiling point: 276.04 °C · 276.04°C (rough estimate)
Density: 1.3682 · 1.3682 (rough estimate)
refractive index: 1.65 · 1.6500 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 2.97 · 2.97±0.37(Predicted)
form: Powder
color: Yellow
InChIKey: BGMZTBKXOFFTBJ-UHFFFAOYSA-N
CAS DataBase Reference: 22280 · 22280-62-2(CAS DataBase Reference)
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H312-H332-H335-H315-H319
Precautionary statements: 264 · P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes: Xn,Xi
Risk Statements: 36 · 36/37/38-20/21/22
Safety Statements: 36 · 36/37/39-26-22-36
HazardClass: 6.1 · 6.1
HS Code: 29333999 · 29333999

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302 (33.3%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (33.3%)

Safety data

hs_code: 29333999
risk_code: 36/37/38-20/21/22
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xn,Xi
safety_code: 36/37/39-26-22-36
hazard_class: 6.1
Hazard statements: H302-H312-H332-H335-H315-H319
Precautionary statements: P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P304+P340-P305+P351+P338-P405-P501a

Chemistry & industry

Applications · 1 item

Uses2-Amino-6-methyl-5-nitropyridine serves as a precursor for synthesizing the imidazo[1,2-a]pyridine derivative 5-methyl-6-nitroimidazo[1,2-a]pyridine via reaction with chloroacetaldehyde in ethanol, and is also employed to construct the 5-substituted pyrrolo[3,2-b]pyridine nucleus[6][7].