Completing data — usually done within a minute
Basic information
- Standard SMILES
CCOC(=O)NNc1ccc(N(CC)CC(C)O)nn1- InChIKey
QLTVVOATEHFXLT-UHFFFAOYSA-N- Molecular formula
- C12H21N5O3
- Average molar mass
- 283.332 g/mol
- Monoisotopic mass
- 283.16443953
Names & identifiers
- Preferred name
- Cadralazine
- IUPAC
- Ethyl 2-{6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl}hydrazine-1-carboxylate
- English name
- Cadralazine
- Molecular formula
- C12H21N5O3
- Molecular weight
- 283.33
Names & synonyms
DC-26DC 826CadralISF-469CadrilanCadratenPresmodeISF 2469CGP 18684ECadralazine
Database identifiers
- CAS
64241-34-5- PubChem CID
- 2515
- DTXSID
DTXSID4048725- ChEMBL
CHEMBL2106561- ChEBI
CHEBI:31331- UNII
- 8T96I3U713
- Nikkaji
- J69.473H
Properties
Physicochemical properties
- Melting point
- 160 · 160-162°
- Boiling point
- 425.88 °C · 425.88°C (rough estimate)
- Density
- 1.1585 · 1.1585 (rough estimate)
- refractive index
- 1.65 · 1.6500 (estimate)
- storage temp.
- 2 · 2-8°C
- solubility
- 250 mg/mL · DMSO : 250 mg/mL (882.36 mM; ultrasonic and warming and heat to 60°C)
- form
- Solid
- pka
- 6 · 6.0(at 25℃)
- color
- White to off-white
- CAS DataBase Reference
- 64241 · 64241-34-5
- FDA UNII
- 8 T96I3U713 · 8T96I3U713
- ATC code
- 2 DB04 · C02DB04
- Toxicity
- 50 in · LD50 in rats, dogs (mg/kg): 269, approx 400 i.v.; 2060, >2000 orally (Semeraro); in mice (mg/kg): 700 i.p. (Parravicini)
Safety & regulation
Safety data
- Toxicity
- LD50 in rats, dogs (mg/kg): 269, approx 400 i.v.; 2060, >2000 orally (Semeraro); in mice (mg/kg): 700 i.p. (Parravicini)
Chemistry & industry
Applications
DescriptionCadralazine is a vasodilatory antihypertensive reportedly better-tolerated and longer-acting than hydralazine. It is useful as a second-line treatment in the management of hypertension.
UsesCadralazine relaxes arterial smooth muscle, thereby reducing peripheral vascular resistance and lowering blood pressure. It is used for hypertension.
Upstream & downstream products
Upstream raw materials
Suppliers29 total
沈阳中申泽康生物医学技术研究有限公司024-88590548 18698872706 · [email protected]
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LGM Pharma1-(800)-881-8210 · [email protected]
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Alfa Chemistry+1-5166625404 · [email protected]
晶墨(厦门)生物科技有限公司13621943973; 13621943973 · [email protected]
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陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
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Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd+86-18341751992 +86-15382112998 · [email protected]
江苏艾康生物医药研发有限公司025-58859352 13913916777 · [email protected]
ATK CHEMICAL COMPANY LIMITED+undefined-21-51877795 · [email protected]
Aladdin Scientific[email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 18917919676 · [email protected]
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济南九黎生物科技有限公司15865264761 · [email protected]
北京索莱宝科技有限公司17801761073 18101056239 · [email protected]
Additional notes
DefinitionChEBI: Cadralazine is an organic molecular entity.
Related reactions
2 records
Linked notes
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