Basic information
- CAS
1982-67-8- Standard SMILES
CS(=N)(=O)CCC([NH3+])C(=O)[O-]- InChIKey
SXTAYKAGBXMACB-UHFFFAOYSA-N- Molecular formula
- C5H12N2O3S
- Average molar mass
- 180.23 g/mol
- Monoisotopic mass
- 180.05686342
Overview
methionine sulfoximine has been reported in Rourea minor, Cnestis polyphylla, and other organisms with data available.
Names & identifiers
- Preferred name
- (2R)-2-azaniumyl-4-(methylsulfonimidoyl)butanoate
- IUPAC
- 2-azaniumyl-4-(methylsulfonimidoyl)butanoate
- English name
- DL-Methionine DL-sulfoximine
- Molecular formula
- C5H12N2O3S
- Molecular weight
- 180.23
Names & synonyms
(2R)-2-azaniumyl-4-(methylsulfonimidoyl)butanoateCNESTINEdl-sulfoximinAURORA KA-705METHIONINESULPHOXIMEmethioninesulfoximineDL-METHIONINE SULFOXIMINEDL-LOBAMINE-DL-SULFOXIMINEdl-methionine-dl-sulfoximinL-METHIONINE-RS-SULPHOXIMINEDL-Methionine DL-sulfoximine
Database identifiers
- CAS
1982-67-8- PubChem CID
- 25201243
Properties
Computed structural properties
- XLogP
- -1.2
- Topological polar surface area
- 117 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 239
Physicochemical properties
- Melting point
- 214 · 214-218 °C (decomp)
- Boiling point
- 352.2 · 352.2±52.0 °C(Predicted)
- Density
- 1.215 · 1.215 (estimate)
- refractive index
- 1.643 · 1.6430 (estimate)
- storage temp.
- 2 · 2-8°C
- form
- Solid
- color
- White to off-white
- FDA UNII
- 9 P6YZ6JX9 · M9P6YZ6JX9
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 319 · H319-H315-H335
- Precautionary statements
- 264 · P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- rtecs
- WS3560000
- hs_code
- 29252900
- Toxicity
- mouse,LD50,intraperitoneal,218mg/kg (218mg/kg),Proceedings of the Society for Experimental Biology and Medicine. Vol. 94, Pg. 12, 1957.
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Hazard statements
- H319-H315-H335
- Precautionary statements
- P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Pharmacology
Cellular LocationsCytoplasm
Applications
UsesMethionine sulfoximine (2-Amino-4-(S-methylsulfonimidoyl)butanoic acid) is an irreversible inhibitor of glutamine synthetase with convulsive effects. Methionine sulfoximine is able to affect the metabolism of glutamate and glutamine, which may provide important insights in neurobiological research. Methionine sulfoximine has also been used to study mechanisms related to epilepsy and its inhibitory potential[1].
Suppliers16 total
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
韶远科技（上海）有限公司4000665055 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
风咏生物（AbMole）021-10000000 13000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
深圳市丽晶生化科技有限公司0755-85201366 18938635012 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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