N,N'-bis(3-aminopropyl)ethylenediamine
Basic information
- CAS
10563-26-5- Standard SMILES
NCCCNCCNCCCN- InChIKey
RXFCIXRFAJRBSG-UHFFFAOYSA-N- Molecular formula
- C8H22N4
- Average molar mass
- 174.29 g/mol
- Monoisotopic mass
- 174.18444672
Overview
3,2,3-tetramine is a tetramine and a polyazaalkane.
Names & identifiers
- Preferred name
- N,N'-bis(3-aminopropyl)ethylenediamine
- IUPAC
- N'-[2-(3-aminopropylamino)ethyl]propane-1,3-diamine
- English name
- N,N'-Bis(3-aminopropyl)ethylenediamine
- Molecular formula
- C8H22N4
- Molecular weight
- 174.29
Names & synonyms
10563-26-5N,N'-Bis(3-aminopropyl)ethylenediamine1,5,8,12-Tetraazadodecane1,3-Propanediamine, N,N''-1,2-ethanediylbis-N,N'-Bis(3-aminopropyl)-1,2-diaminoethaneN,N'-Bis(gamma-aminopropyl)diaminoethaneN,N'-Di(3-aminopropyl)-1,2-ethylenediamine1,3-Propanediamine, N,N''-ethylenebis-EINECS 234-147-9NSC 1808230EXW8894XX4,7-diazadecane-1,10-diamine
Show more names
TATA1,2-BIS(3-AMINOPROPYLAMINO)ETHANEN1,N1'-(Ethane-1,2-diyl)bis(propane-1,3-diamine)N'-[2-(3-aminopropylamino)ethyl]propane-1,3-diamineN4-AMINEFentacat 263,2,3-tetramineN,N'-BIS(3-AMINOPROP
N4 AMINENSC-180823DTXSID2065127EC 234-147-91,3-Propanediamine, N1,N1'-1,2-ethanediylbis-3,2,3-TETBIS(3-AMINOPROPYL)ETHYLENEDIAMINE, N,N'-N,N'-BIS(.GAMMA.-AMINOPROPYL)DIAMINOETHANE
Database identifiers
- CAS
10563-26-5- PubChem CID
- 25378
- DTXSID
DTXSID2065127- ChEMBL
CHEMBL259148- ChEBI
CHEBI:39476- UNII
- 0EXW8894XX
- EC Number
- 234-147-9
- Nikkaji
- J226.991K
Properties
Computed structural properties
- XLogP
- -1.8
- Topological polar surface area
- 76.1 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 9
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 67.5
Experimental & physicochemical properties
Chemical ClassesNitrogen Compounds -> Amines, Aliphatic
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description
Large Crystals; Liquid
Clear colorless to pale yellow liquid; [Acros Organics MSDS]
Physicochemical properties
- Melting point
- -1.5 °C · -1.5 °C
- Boiling point
- 150 · 150-160 °C5 mm Hg(lit.)
- Density
- 0.952 g/mL · 0.952 g/mL at 25 °C(lit.)
- vapor pressure
- 2.2 hPa · 2.2hPa at 20℃
- refractive index
- 20 · n20/D 1.491(lit.)
- Flash point
- 230 °F · >230 °F
- storage temp.
- 2 · Keep in dark place,Sealed in dry,2-8°C
- form
- liquid
- pka
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (98.6%): Harmful if swallowed [Warning Acute toxicity, oral]
P260, P261, P262, P264, P264+P265, P270, P271, P272, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 218 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Chemical: 1,3-Propanediamine, N,N''-1,2-ethanediylbis-
1,3-Propanediamine, N1,N1'-1,2-ethanediylbis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,3-Propanediamine, N1,N1'-1,2-ethanediylbis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: N,N'-bis(3-aminopropyl)ethylenediamine (EC: 234-147-9)
1,3-Propanediamine, N,N''-1,2-ethanediylbis-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards Summary
Causes burns; May cause skin sensitization; Harmful by ingestion; Toxic by skin absorption; [ECHA REACH Registrations] A skin sensitizer in Buehler test of guinea pigs; Decreased corpora lutea, implantations, gestation index, and mean litter sizes, 5 of 9 pregnant females delivering offspring, and histopathological changes of the lung, stomach, spleen, kidney, adrenals, and eyes observed in oral study of rats at 300 mg/kg/day; [EPA - TSCATS] Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; [Acros Organics MSDS]
Chemistry & industry
Uses & manufacturing
UsesUsed as an intermediate; [EPA - TSCATS] Used in cleaning agents, as a laboratory reagent, monomer and auxiliary in polymerization reactions, and to make large scale chemicals; [ECHA REACH Registrations]
U.S. Production2023: 1,000,000 - <5,000,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesUV stabilizer
General Manufacturing Information
Computer and Electronic Product Manufacturing
1,3-Propanediamine, N1,N1'-1,2-ethanediylbis-: ACTIVE
Applications
UsesThe condensation reaction of 1,2-bis(3-aminopropylamino)ethane [3,3′-ethylenediiminodipropylamine] with 4,6-dibenzofurandicarbaldehyde was studied.
General DescriptionThe condensation reaction of 1,2-bis(3-aminopropylamino)ethane [3,3′-ethylenediiminodipropylamine] with 4,6-dibenzofurandicarbaldehyde was studied.
Additional notes
DefinitionChEBI: 3,2,3-tetramine is a tetramine and a polyazaalkane.
Related reactions
6 records
Compound notes
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