Basic information
- CAS
107615-77-0- Standard SMILES
CCCCCC(=O)CC[C@@H]1[C@@H](C/C=C\CCCC(=O)O)[C@@H](O)C[C@@H]1O- InChIKey
VKTIONYPMSCHQI-KGILNJEGSA-N- Molecular formula
- C20H34O5
- Average molar mass
- 354.5 g/mol
- Monoisotopic mass
- 354.24062418
Overview
11beta-13,14-dihydro-15-keto-PGF2alpha is a prostanoid.
Names & identifiers
- Preferred name
- 11beta-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2alpha
- IUPAC
- (Z)-7-[(1R,2R,3S,5S)-3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid
- English name
- 11beta-13, 14-Dihydro-15-keto prostaglandin f2alpha
- Molecular formula
- C20H34O5
- Molecular weight
- 354.48
Names & synonyms
107615-77-011beta-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2alpha(Z)-7-[(1R,2R,3S,5S)-3,5-dihydroxy-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid9S,11R-dihydroxy-15-oxo-5Z-prostenoic acid11beta-13,14-dihydro-15-keto PGF2alpha11|A-13,14-dihydro-15-keto Prostaglandin F2|A11beta-13,14-dihydro-15-keto Prostaglandin F2alpha11beta-dhk-PGF2a11beta-dhk-PGF2alphaorb2283653CHEBI:140931DTXSID301348020
Show more names
VKTIONYPMSCHQI-KGILNJEGSA-N11β-13,14-dihydro-15-keto Prostaglandin F2α9ALPHA, 11BETA-DIHYDROXY-15-OXO-PROST-5Z-EN-1-OIC ACID
LMFA03010203HY-113208APD02057511beta-13,14-dihydro-15-keto-PGF2alphaCS-0065499T84577SR-01000946859SR-01000946859-1
Database identifiers
- CAS
107615-77-0
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 94.8 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 13
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 432
Experimental & physicochemical properties
LipidsFatty Acyls [FA] -> Eicosanoids [FA03] -> Prostaglandins [FA0301]
Physicochemical properties
- solubility
- 10 mM · 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Danger
- Hazard statements
- 225 · H225-H319-H336
- Precautionary statements
- 210 · P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS07
- Hazard statements
- H225-H319-H336
- Precautionary statements
- P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Chemistry & industry
Applications
Description11β-13,14-dihydro-15-keto PGF2α is a metabolite of PGD2 in the 15-hydroxy PGDH pathway.1,2 Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes.1 Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but not 11β-13,14-dihydro-15-keto PGF2α.2 Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α, via 11β-PGF2α, in the presence of NAD+ and NADP+.2
Uses11β-13,14-Dihydro-15-keto Prostaglandin F2α is the deviative of 13,14-Dihydro-15-keto PGF2a (HY-113208), which is an endogenous metabolite present in Blood that can be used for the research of Pregnancy[1][2].
Suppliers4 total
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
ChemeGen 中国18818260767 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Additional notes
DefinitionChEBI: 11beta-13,14-dihydro-15-keto-PGF2alpha is a prostanoid.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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