Basic information
- CAS
5942-95-0- Standard SMILES
NC(=O)C1(N2CCCCC2)CCN(CCCN2c3ccccc3CCc3ccccc32)CC1- InChIKey
NWPJLRSCSQHPJV-UHFFFAOYSA-N- Molecular formula
- C28H38N4O
- Average molar mass
- 446.6 g/mol
- Monoisotopic mass
- 446.30456185
Overview
Carpipramine is a dibenzooxazepine.
Names & identifiers
- Preferred name
- Carpipramine
- IUPAC
- 1-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamide
- English name
- Carpipramine
- Molecular formula
- C28H38N4O
- Molecular weight
- 446.63
Names & synonyms
carpipramineCarbadipimidine5942-95-0CarpipraminaBay b 4343 bCarpipraminum8AFK6F91EQDTXSID402081495-(3-(4-Piperidino-4-carbamoylpiperidino)propyl)-10,11-dihydro-5(H)-dibenz(b,f)azepineRefChem:123810DTXCID10130640227-700-0
Show more names
PZ-1511PrazinilBay-b 4343bcarpipramine USP/EP/BP10,11-Dihydro-5-[3-(4-piperidino-4-carbamoylpiperidino)propyl]-5H-dibenz[b,f]azepine1'-[3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)propyl](1,4'-bipiperidine)-4'-carboxamide[1,4'-Bipiperidine]-4'-carboxamide, 1'-[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-1-[3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]-4-(1-piperidinyl)piperidine-4-carboxamide
Carpipramine [INN]1-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl]-4-piperidin-1-ylpiperidine-4-carboxamideCarpipramine (INN)Carpipraminum [INN-Latin]Carpipramina [INN-Spanish]EINECS 227-700-0UNII-8AFK6F91EQBRN 0502521
Properties
Computed structural properties
- XLogP
- 4.5
- Topological polar surface area
- 52.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 6
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 616
Physicochemical properties
- Boiling point
- 555.94 °C · 555.94°C (rough estimate)
- Density
- 1.0748 · 1.0748 (rough estimate)
- refractive index
- 1.55 · 1.5500 (estimate)
- FDA UNII
- 8 AFK6F91EQ · 8AFK6F91EQ
- Toxicity
- 50 oral · LD50 oral in rat: 1025mg/kg
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 oral in rat: 1025mg/kg
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
Suppliers5 total
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
玺标（上海）科技有限公司18512111473 18512111473 · [email protected]
湖北扬信医药科技有限公司0714-3999001 19171453112 · [email protected]
Dideu Industries Group Limited+86-29-81148696 +86-15129568250 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
Additional notes
DefinitionCarpipramine is a first-generation (typical) antipsychotic drug that belongs to the iminodibenzyl class indicated for the treatment of schizophrenia, particularly for negative symptoms. It has been found that carpipramine and its pharmaceutically acceptable salts possess antagonist properties with respect to D2 and 5-HT2 receptors and are also useful in the treatment of depression, anxiety, and sleep disorders. It can induce insomnia, agitation, and extrapyramidal motor side effects, but it generally displays low toxicity.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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