HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromide ion
Br- · BROMIDE ION · 6XY · 4LJ · 1d2v · VLA-2 · VLAA2 · HPA-5
Identifiers & Physical Properties
| CAS No. | 24959-67-9 |
|---|---|
| Molecular formula | Br- |
| Average molar mass | 79.9 g/mol |
| Monoisotopic mass | 78.91834 g/mol |
| SMILES | [Br-] |
| InChIKey | CPELXLSAUQHCOX-UHFFFAOYSA-M |
| PubChem CID | 259 |
| ChEMBL | CHEMBL1231461 |
| ChEBI | CHEBI:15858 |
| DTXSID | DTXSID6043967 |
Chemical & Physical Properties
| XLogP | 1 |
|---|---|
| Topological polar surface area | 0 |
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 1 |
| Rotatable bonds | 0 |
| Heavy atoms | 1 |
| Formal charge | -1 |
| Complexity | 0 |
| Chemical classes | Major ion |
| Solubility | 35 mg/mL at 20 °C |
| Melting point | -7.25 °C |
| Physical Description | Liquid |
| Storage conditions | 2-8°C |
| Physical state | Liquid |
| CAS DataBase Reference | 24959-67-9(CAS DataBase Reference) |
| FDA UNII | 952902IX06 |
| EPA Substance Registry System | Bromide (24959-67-9) |
| Safety statements (S) | 22-24/25 |
| Water hazard class (WGK) | 3 |
Safety & Regulations
| Treatment | In case of acute exposure, bromide salts should be washed with water from any areas of dermal or ocular contact. If inhaled, treatment is mainly symptomatic and may include maintaining an adequate airway, administering oxygen, antibronchospasm therapy, and/or antibiotics. (L626) |
|---|---|
| Health effects | The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627) |
| Exposure routes | Oral (L626)inhalation (L626)dermal (L626) |
| Toxicity summary | The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543) |
| Signs and Symptoms | The bromide ion is a central nervous system depressant producing ataxia, slurred speech, tremor, nausea, vomiting, lethargy, dizziness, visual disturbances, unsteadiness, headaches, impaired memory and concentration, disorientation and hallucinations. (L626, L627) |
| Carcinogen Classification | No indication of carcinogenicity (not listed by IARC). (L135) |
| Toxicity Data | LD50: 85.2 ppm (Intraperitoneal, Rat) (A542) LD50: 2600 mg/kg (Oral, Rat) (A542) LC50: 750 ppm over 9 minutes (Inhalation, Mouse) (A542) |
| USGS Health-Based Screening Levels for Evaluating Water-Quality | BromideMajor ionSmith, C.D. and Nowell, L.H., 2024. Health-Based Screening Levels for evaluating water-quality data (3rd ed.). DOI:10.5066/F71C1TWP |
| Water hazard class (WGK) | 3 |
| Safety statements (S) | 22-24/25 |
Applications & Uses
Uses
BROMIDE is used as medications for ENT (Ear, Nose, and Throat).