Basic information
- CAS
15148-80-8- Standard SMILES
Cc1ccc(Cl)c(OCC(O)CNC(C)(C)C)c1.Cl- InChIKey
WJUUZHQWGKSLIJ-UHFFFAOYSA-N- Molecular formula
- C14H23Cl2NO2
- Average molar mass
- 308.2 g/mol
- Monoisotopic mass
- 307.1105844
Overview
Bupranolol hydrochloride is an aromatic ether.
Names & identifiers
- Preferred name
- 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-((1,1-dimethylethyl)amino)-, hydrochloride (1:1)
- IUPAC
- 1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol;hydrochloride
- English name
- 3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride
- Molecular formula
- C14H22ClNO2.ClH
- Molecular weight
- 308.24
Names & synonyms
bupranolol hydrochlorideBupranolol HCl15148-80-8BetadranPanimitLooserB 1312DTC2G3GDPLDTXSID50904544B-1312RefChem:1064253DTXCID701333683
Show more names
KL 255dl-KL 255(-)-KL 255SKF 16805A(+-)-Kl 255
(2RS)-3-(2-Chloro-5-methylphenoxy)-1-(1,1-dimethylethyl)aminopropan-2-ol monohydrochloride2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-((1,1-dimethylethyl)amino)-, hydrochloride (1:1)239-208-3BetadrenolBupranolol hydrochloride [JAN]Bupranolol (hydrochloride)1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride3-(tert-Butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride
Database identifiers
- CAS
15148-80-8- PubChem CID
- 27072
- DTXSID
DTXSID50904544- ChEBI
CHEBI:31323- UNII
- DTC2G3GDPL
- EC Number
- 239-208-3
Properties
Computed structural properties
- Topological polar surface area
- 41.5 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 6
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 242
Physicochemical properties
- Melting point
- 220 · 220-222°
- FDA UNII
- 2 G3GDPL · DTC2G3GDPL
Chemistry & industry
Applications
UsesBupranolol hydrochloride is a non-selective β-adrenergic blocker with potent membrane stabilizing activity. Bupranolol hydrochloride is able to significantly modulate the contractile activity of the non-pregnant human uterus. Bupranolol hydrochloride showed significant effects on spontaneous uterine contractions in an in vitro study in patients with ovarian cancer. Bupranolol hydrochloride is similar in potency to propranolol, another β-adrenergic blocker. Bupranolol hydrochloride is rapidly and completely absorbed in vivo, and its major metabolite is carboxybupranolol[1].
Suppliers5 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
陕西缔都新材料有限公司029-63373950 17392216152 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Additional notes
DefinitionChEBI: Bupranolol hydrochloride is an aromatic ether.
Related reactions
1 records
Compound notes
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