Basic information
- CAS
66-84-2- Standard SMILES
Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O- InChIKey
QKPLRMLTKYXDST-NSEZLWDYSA-N- Molecular formula
- C6H14ClNO5
- Average molar mass
- 215.63 g/mol
- Monoisotopic mass
- 215.05605023
Overview
See also: Glucosamine Hydrochloride (annotation moved to).
Names & identifiers
- Preferred name
- (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride
- IUPAC
- (3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol;hydrochloride
- English name
- D-Glucosamine hydrochloride
- Molecular formula
- C6H14ClNO5
- Molecular weight
- 215.63
Names & synonyms
1078691-95-82-Amino-2-deoxyglucose hydrochloride(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride2-Amino-2-deoxyglucose (hydrochloride)D(+)-Glucosamine hydrochloride(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol;hydrochlorideCAS-66-84-2SMR000718786C6H14ClNO5EN300-57128Glucosamine hydrochloride; 2-Amino-2-deoxy-d-glucopyranose hydrochlorideNCGC00094688-01
Show more names
GLUCOSAMINE HYDROCHLORIDEGLUCOSAMINE HCLD-GLUCOSAMINE HCL2-AMINO-2-DEOXY-D-GLUCOSE HYDROCHLORIDEGlucosamine for system suitability CRSD-GLCN HCLD-Glucosamine Salt(+)-2-Amino-2-deoxy-D-glucose hydrochloride2-amino-2-deoxy-D-glucose hydrochloride (1:1)2-[15N]aMino-2-deoxy-d-[UL-13C6] glucose hydrochloride
GlcN.HClglucosamine HCl saltGlucosamine-HCl salt2-Amino-2-deoxy-D-glucopyranose Hydrochloride66-84-2 (HCl)glucosamine-hydrochloride2-Amino-2-deoxyglucose HClSCHEMBL21213
Properties
Computed structural properties
- Topological polar surface area
- 116 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 1
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 155
Experimental & physicochemical properties
Solubility>32.3 [ug/mL] (The mean of the results at pH 7.4)
Physicochemical properties
- Melting point
- 190 · 190-194 °C (dec.)(lit.)
- alpha
- 72.5 · 72.5 º (c=2, H2O, 5hrs.)
- refractive index
- 72 ° · 72 ° (C=1, H2O)
- storage temp.
- 2 · 2-8°C
- solubility
- 2 O: · H2O: 0.1 g/mL, clear, colorless
- form
- crystalline
- color
- White
- biological source
- Aspergillus nigermaize fruit
- Water Solubility
- soluble
- Merck
- 14 · 14,4458
- BRN
- 4157370 · 4157370
- Stability
- Stable. Incompatible with strong oxidizing agents. Combustible.
- Cosmetics Ingredients Functions
- ANTISTATICHAIR CONDITIONING
Safety & regulation
Safety data
- F
- 3-10
- wgk
- 2
- tsca
- TSCA listed
- rtecs
- LZ6665000
- hs_code
- 29329985
- risk_code
- 21-36/38-46-62-63
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- F,Xi,Xn
- hazard_note
- Highly Flammable
- safety_code
- 24/25-53-36/37-26-25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- REACH Registrations
- Inactive
- Precautionary statements
- P261-P271-P280
Chemistry & industry
Applications
Usesglucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties.
UsesNovel application of glucosamine is to prepare medical agent for treating vertigo. It is used as food ingredients and additives, raw material for anti cancer and antibiotic drugs.
UsesNovel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties.
General DescriptionD-Glucosamine hydrochloride is frequently employed as a dietary supplement to support joint health and alleviate inflammation. It is recognized for its role in the biosynthesis of glycosaminoglycans and subsequently in the formation of cartilage and joint tissues.
Preparation methods
PreparationA novel method for preparing glucosamine hydrochloride using chitosan includes the following steps: hydrochloric acid hydrolysis, mother liquor cooling crystallization, filtrate concentration, concentrated solution cooling crystallization, decolorization, decolorized solution crystallization, and purification. In this method, after hydrolysis and filtrate concentration, cooling crystallization is performed first to separate D-glucosamine hydrochloride from the solution with a high impurity content. This also allows oils and impurities to precipitate from the solution and suspend on the top layer of the crystals, facilitating their removal.
Upstream & downstream products
Upstream raw materials
Downstream products
Related reactions
70 records
Compound notes
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