2-Bromo-1,1,1,2,3,3,3-heptafluoropropane

Uses2-Bromoheptafluoropropane is a key raw material intermediate for the synthesis of Broflanilide, which is a meta-diamide insecticide for the control of common crop pests, including Lepidoptera, Coleoptera, termites, mosquitoes and flies. Current studies show that Broflanilide has reported excellent insecticidal activity against larvae and adults.

Preparation1,1,1,2,3,3,3-heptafluoropropane was mixed with bromine at a molar ratio of 1 to 5:1 and subjected to a multi-stage bromination reaction. Chlorine gas was introduced between each stage of the bromination reaction. The resulting reaction product was washed with water, washed with alkali, and distilled to obtain 2-bromoheptafluoropropane.