Basic information
- CAS
14913-33-8- Standard SMILES
[Cl][Pt+2][Cl].[NH2-].[NH2-]- InChIKey
DQLATGHUWYMOKM-UHFFFAOYSA-L- Molecular formula
- Cl2H4N2Pt
- Average molar mass
- 298.03 g/mol
- Monoisotopic mass
- 296.939948
Names & identifiers
- Preferred name
- Cantide + Cisplatin
- IUPAC
- azanide;dichloroplatinum(2+)
- English name
- trans-Dichlorodiamineplatinum(II)
- Molecular formula
- Cl2H6N2Pt
- Molecular weight
- 300.04
Names & synonyms
26035-31-4Cantide + CisplatinRefChem:331616cis-DiaminedichloroplatinumPlatinum, diamminedichloro-NCGC00090759-01DTXCID90227183CAS-15663-27-1Platinum,diamminedichloro-cis-Dichlorodiamine platinumBiocisplatinumNeuro_000055
Show more names
transplatinTRANS-DIAMMINEDICHLOROPLATINUM(II)PLATINOLtrans-dichlorodiammineplatinumCPDCCIS-DDPPLATINEXBRIPLATINCISPLATYLCISMAPLAT
SCHEMBL5838cis-Platinum diamminedichloridecis-diaminedichloroplatinum(II)orb1308163orb3141228cis-Diammine-dichloroplatinum(II)HMS3268F06HMS3654E14
Database identifiers
- CAS
14913-33-8、15663-27-1、26035-31-4- PubChem CID
- 2767
- DTXSID
DTXSID4024983- EC Number
- 247-419-7
Properties
Computed structural properties
- Topological polar surface area
- 2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 5
- Formal charge
- 0
- Complexity
- 7.6
Experimental & physicochemical properties
LogP-2.19
Melting Point270 °C
Physical DescriptionSolid
Physicochemical properties
- Melting point
- 340 °C · 340 °C (dec.)(lit.)
- storage temp.
- 2 · 2-8°C
- solubility
- DMSO (Sparingly)
- form
- crystalline
- pka
- 5.63 · 5.63
- color
- yellow
- Water Solubility
- Soluble in dimethylsulfoxide and dimethylformamide. Slightly soluble in water.
- Exposure limits
- 0.002 mg/m3NIOSH: · ACGIH: TWA 0.002 mg/m3NIOSH: IDLH 4 mg/m3; TWA 0.002 mg/m3
- Major Application
- pharmaceutical (small molecule)
- InChI
- InChI=1S/2ClH.2H2N.Pt/h2*1H;2*1H2;/q;;2*-1;+4/p-2
- InChIKey
- DQLATGHUWYMOKM-UHFFFAOYSA-L
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 10-21
- wgk
- 3
- rtecs
- TP2455000
- ridadr
- UN 3288 6.1/PG 2
- hs_code
- 28439000
- Toxicity
- mouse,LD50,intraperitoneal,27mg/kg (27mg/kg),Chemico-Biological Interactions. Vol. 5, Pg. 415, 1972.
- risk_code
- 45-25-41-68-42/43-40-23/24/25
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS08
- hazard_code
- T,Xn
- safety_code
- 53-26-39-45-36/37-24-23
- hazard_class
- 6.1(a)
- Storage Class
- 11 - Combustible Solids
- packing_group
- II
- Hazard statements
- H317-H318-H334
- Hazard Classifications
- Eye Dam. 1Resp. Sens. 1Skin Sens. 1
- Precautionary statements
- P280-P302+P352-P305+P351+P338+P310
- Hazardous Substances Data
- 14913-33-8(Hazardous Substances Data)
Chemistry & industry
Pharmacology
ATC CodeL01XA01
Cellular LocationsCytoplasm
Uses & manufacturing
General Manufacturing InformationPlatinum, diamminedichloro-: INACTIVE
Applications
UsesTransplatin is the trans stereoisomer impurity of Cisplatin (C499500), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
UsesTransplatin is the trans stereoisomer impurity of trans-Dichlorodiamineplatinum(II), an antineoplastic used in the treatment of sarcomas, some carcinomas, lymphomas, and germ cell tumors. Transplatin binds to DNA but does not exhibit the same useful pharmacological effect as its cis stereoisomer.
Suppliers100 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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