Erythrosine sodium
Basic information
- CAS
16423-68-0- Standard SMILES
O=C([O-])c1ccccc1-c1c2cc(I)c(=O)c(I)c-2oc2c(I)c([O-])c(I)cc12.[Na+].[Na+]- InChIKey
IINNWAYUJNWZRM-UHFFFAOYSA-L- Molecular formula
- C20H6I4Na2O5
- Average molar mass
- 879.9 g/mol
Overview
Erythrosin B is an organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid. It has a role as a fluorescent dye. It contains an erythrosin(2-).
Names & identifiers
- Preferred name
- Erythrosine sodium
- IUPAC
- disodium;2-(2,4,5,7-tetraiodo-3-oxido-6-oxoxanthen-9-yl)benzoate
- English name
- ERYTHROSIN B
- Molecular formula
- C20H8I4O5.2Na
- Molecular weight
- 881.87
Names & synonyms
Erythrosine sodiumDTXSID901015598RefChem:1084261DTXCID601233Benzoic acid, 2-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)-, disodium saltC.I. Acid Red 51E 127Erythrosine BSFood Red No. 3568-63-8Acid red 51C.I. 45430
Show more names
ebsERYTHROSINEERYTHROSINE BTETRAIODOFLUORESCEIN2',4',5',7'-TETRAIODOFLUORESCEIN DISODIUM SALTE12745430Red No. 3ERYTHROCIN BLAKE ERYTHROSINE
disodium;2-(2,4,5,7-tetraiodo-3-oxido-6-oxoxanthen-9-yl)benzoateCHEMBL20281872-(6-hydroxy-2,4,5,7-tetraiodo-3-oxoxanthen-9-yl)benzoic acid, sodium salt, so dium saltIodoeosine Sodium SaltERYTHROSINE [MI]Erythrosine sodium anhydrousSCHEMBL22294SCHEMBL29381889
Database identifiers
- CAS
16423-68-0、568-63-8
Properties
Computed structural properties
- Topological polar surface area
- 89.5 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 31
- Formal charge
- 0
- Complexity
- 796
Experimental & physicochemical properties
CosmeticsHair dyeing
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Physicochemical properties
- Melting point
- 142 · 142~144℃
- Density
- 0.98 · 0.98
- bulk density
- 470 kg/m3 · 470kg/m3
- vapor pressure
- 0 Pa · 0Pa at 25℃
- Flash point
- 285 ℃ · 285℃
- storage temp.
- room temp
- solubility
- 100 g/l · 100g/l
- Colour Index
- 45430 · 45430
- pka
- 4.1 · 4.1(at 25℃)
- form
- Fine Powder
- color
- Deep red to brown
- PH
- 6 · 6-7 (10g/l, H2O, 20℃)
- PH Range
- 0 · 0(yellow)-3.6(red)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory InformationErythrosine sodium: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Toxicology
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
Safety data
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- LM5950000
- ridadr
- UN3077
- hs_code
- 32129000
- Toxicity
- LD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell)
- risk_code
- 22
- Signal word
- Warning
- Symbol(GHS)
Chemistry & industry
Uses & manufacturing
Use ClassificationCosmetics -> Hair dyeing
Applications
DescriptionFD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1 .
Usesantibacterial
UsesErythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine.
UsesErythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products.
UsesBiological stain; color additive.
General DescriptionErythrosin B (C.I. 45430)for microscopy Certistain, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
Related reactions
2 records
Compound notes
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