Basic information
- CAS
1223-36-5- Standard SMILES
CCN(CC)CCNC(=O)COc1ccc(Cl)cc1- InChIKey
UORGKWWJEQDTGX-UHFFFAOYSA-N- Molecular formula
- C14H21ClN2O2
- Average molar mass
- 284.78 g/mol
- Monoisotopic mass
- 284.1291556
Overview
Clofexamide is a small molecule drug. Clofexamide has a monoisotopic molecular weight of 284.13 Da.
Names & identifiers
- Preferred name
- 2-(4-Chlorophenoxy)-N-(2-(diethylamino)ethyl)acetamide
- IUPAC
- 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
- English name
- clofexamide
- Molecular formula
- C14H21ClN2O2
- Molecular weight
- 284.78
Names & synonyms
Clofexamide1223-36-5AmichlopheneClofexamidaANP 246ClofexamidumDTXSID60464242-(4-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamideANP-246071P4J77HF2-(p-Chlorophenoxy)-N-(2-(diethylamino)ethyl)acetamideN-(2-Diethylaminoethyl)-4-chlorophenoxyacetamide
Show more names
ANP246NP-246IEM-455Acetamide, 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]-
2-(4-chlorophenoxy)-N-(2-(diethylamino)ethyl)acetamideDTXCID40264242-(p-Chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamideRefChem:909318214-951-6ChlofexamideANP 246; Amichlophene; ChlofexamideNCGC00164540-01
Database identifiers
- CAS
1223-36-5- PubChem CID
- 28554
- DTXSID
DTXSID6046424- ChEMBL
CHEMBL2106515- UNII
- 071P4J77HF
- EC Number
- 214-951-6
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 41.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 8
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 252
Physicochemical properties
- Melting point
- 45 °C · 45 °C
- Boiling point
- 124.5 °C · 124.5°C (rough estimate)
- Density
- 1.1742 · 1.1742 (rough estimate)
- refractive index
- 1.52 · 1.5200 (estimate)
- pka
- 14.19 · 14.19±0.46(Predicted)
- FDA UNII
- 71 P4J77HF · 071P4J77HF
- Toxicity
- 50 oral · LD50 oral in rat: 1040mg/kg
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 oral in rat: 1040mg/kg
Chemistry & industry
Applications
UsesClofexamide (ANP 246; Amichlophene) is a potent antidepressant agent. Clofexamide also shows anti-inflammatory activity[1][2].
Upstream & downstream products
Upstream raw materials
Suppliers9 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
韶关市启程生物科技有限公司18122215013 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
苏州致信生物科技有限公司0512-65118909 18100677375 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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