Basic information
- CAS
2880-89-9- Standard SMILES
O=c1[nH]c(=O)n(C2OC(CO)C(O)C2O)cc1Cl- InChIKey
LDCUBKKZHSYQTJ-UHFFFAOYSA-N- Molecular formula
- C9H11ClN2O6
- Average molar mass
- 278.64 g/mol
- Monoisotopic mass
- 278.0305638
Names & identifiers
- Preferred name
- 5-Chloro-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- IUPAC
- 5-chloro-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
- English name
- 5-Chlorouridine
- Molecular formula
- C9H11ClN2O6
- Molecular weight
- 278.65
Names & synonyms
5-chloro-1-[3,4-dihydroxy-5-(hydroxymethyl)-2-oxolanyl]pyrimidine-2,4-dione5-chloro-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dioneDTXSID009514425-chloro-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dioneNSC146433AKOS015963322AC-1895NSC-1464335-Chloro-4-hydroxy-1-pentofuranosylpyrimidin-2(1H)-one2,4(1H,3H)-Pyrimidinedione, 5-chloro-1-pentofuranosyl-6-Cl-UNSC 146433
Show more names
5-CHLOROURIDINE5-Chloro-D-uridineUridine, 5-chloro-5-Chlorouridine USP/EP/BP9H-Purine, 2,6-di-4-morpholinyl-9-β-D-ribofuranosyl- (ACI)5-CHLORO-1-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-3H-PYRIMIDINE-2,4-DIONE5-Chloro-1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Properties
Computed structural properties
- XLogP
- -1.1
- Topological polar surface area
- 119 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 2
- Heavy atoms
- 18
- Formal charge
- 0
- Complexity
- 414
Physicochemical properties
- Melting point
- 215 · 215-217°C
- Density
- 1.8 · 1.80±0.1 g/cm3(Predicted)
- storage temp.
- 2 · Sealed in dry,2-8°C
- solubility
- DMSO (Slightly), Methanol, Water (Slightly, Sonicated)
- form
- Solid
- pka
- 7.73 · 7.73±0.10(Predicted)
- color
- White to Off-White
- CAS DataBase Reference
- 2880 · 2880-89-9(CAS DataBase Reference)
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
Safety & regulation
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
Uses5-Chlorouridine is used in method of determining the activity of enzymes converting Cytosine derivatives to Uracil derivatives in cells, tissues and organisms.
Suppliers91 total
上海康恩博医药科技有限公司17510465506 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
Zhengzhou Chemprize Biotech Co., Ltd.+86-86-0371-56768238 +86-15981919713 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
Shaanxi LonierHerb Bio Technology Co Ltd+86-86-+86-86-029-87551862 15002946897 · [email protected]
安徽省旭鑫化工有限公司17312368885 · [email protected]
河南多贝化工有限公司0370-6999054 17550096163 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
清宁生物（江苏博泉生物科技有限公司）19352250998 · [email protected]
普善实业（陕西）有限公司029-81310890 18165209495 · [email protected]
宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]
Related reactions
1 records
Compound notes
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