Butamirate Citrate

HCID 28891CAS 18109-81-4
Substructure searchFind similar structures

Basic information

Standard SMILES
CCC(C(=O)OCCOCCN(CC)CC)c1ccccc1.O=C(O)CC(O)(CC(=O)O)C(=O)O
InChIKey
JVKMHUAWFDGPTF-UHFFFAOYSA-N
Molecular formula
C24H37NO10
Average molar mass
499.6 g/mol
Monoisotopic mass
499.24174638

Overview

See also: Butamirate (has active moiety).

Names & identifiers

Preferred name
Butamirate Citrate
IUPAC
2-[2-(diethylamino)ethoxy]ethyl 2-phenylbutanoate;2-hydroxypropane-1,2,3-tricarboxylic acid
English name
Butamirate citrate
Molecular formula
C24H37NO10
Molecular weight
499.55128

Names & synonyms

Butamirate citrate18109-81-4Abbott 36581HH 197HH-197ABBOTT-36581DTXSID004627067HP51L98RDTXCID8026270RefChem:121976242-006-8Butamyrate
Show more names
PanatusCoughCutSinecond
Butamirate (citrate)Butamirate citrate [USAN]AcodeenSincodeenSincodinSincodixSinecod2-[2-(diethylamino)ethoxy]ethyl 2-phenylbutanoate;2-hydroxypropane-1,2,3-tricarboxylic acid

Database identifiers

CAS
18109-81-4
PubChem CID
28891
DTXSID
DTXSID0046270
ChEMBL
CHEMBL2106133
UNII
67HP51L98R
EC Number
242-006-8

Properties

Computed structural properties

Topological polar surface area
171 Ų
Hydrogen bond donors
4
Hydrogen bond acceptors
11
Rotatable bonds
17
Heavy atoms
35

Physicochemical properties

Melting point
66 · 66-68°C
storage temp.
Hygroscopic, Refrigerator, Under Inert Atmosphere
solubility
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form
Solid
color
White
InChIKey
JVKMHUAWFDGPTF-UHFFFAOYSA-N

Safety & regulation

GHS classification

GHS Classification · 3 items

This chemical does not meet GHS hazard criteria for 100% (2 of 2) of all reports.

Not Classified

Aggregated GHS information provided per 2 reports by companies from 1 notifications to the ECHA C&L Inventory.

Hazard information

Hazard Classes and CategoriesNot Classified

Chemistry & industry

Applications · 3 items

UsesAnxiolytic, Muscle Relaxant

UsesButamirate Citrate is a novel antitussive drug. It is used for the symptomatic treatment of non-productive (dry) cough.

General DescriptionButamirate citrate is a non-opioid antitussive with a central effect on receptors in the brain stem. It has also been reported that it reduces bronchospasm with peripheral effect and has anti-inflammatory and anticholinergic effects. Therefore, it is thought to be effective in cough with both acute and chronic etiology.

Upstream & downstream products

Suppliers48 total

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
江苏艾康生物医药研发有限公司025-58851090 19370895928 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]

Related reactions

0 records
New reaction record

No reaction records under the current filter.

Linked notes

Loading…