Basic information
- CAS
19395-87-0- Standard SMILES
CC(=O)NNC(=O)N1Cc2cc(Cl)ccc2Oc2ccccc21- InChIKey
UETSVHKFTALXNP-UHFFFAOYSA-N- Molecular formula
- C16H14ClN3O3
- Average molar mass
- 331.75 g/mol
- Monoisotopic mass
- 331.072369
Overview
Inhibits the activity of prostaglandins.
Names & identifiers
- Preferred name
- Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
- IUPAC
- N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
- English name
- SC 19220
- Molecular formula
- C16H14ClN3O3
- Molecular weight
- 331.75
Names & synonyms
Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazideDTXSID10941091RefChem:920035DTXCID301369537PDSP1_001724N'-acetyl-8-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazidePDSP2_001707L000545N'-Acetyl-2-chlorodibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazideSC 192202-acetylhydrazide 10(11h)-carboxylic acid8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
Show more names
N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10[11H]-CARBOXY-(2-ACETYL)HYDRAZIDE8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE8-CHLORO-DIBENZO[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDEDibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid,2-acetylhydrazide
Properties
Computed structural properties
- XLogP
- 2.3
- Topological polar surface area
- 70.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 462
Physicochemical properties
- Melting point
- 190 · 190-191 °C (lit.)
- storage temp.
- Store at RT
- solubility
- 10 mg/mL, · DMSO: 10 mg/mL, soluble
- form
- solid
- color
- white
- InChI
- 1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)
- InChIKey
- KNURFLJTOUGOOQ-UHFFFAOYSA-N
- SMILES
- CC(=O)NNC(=O)N1Cc2ccccc2Oc3ccc(Cl)cc13
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- WGK Germany
- 3 · 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationCompounds that inhibit the action of prostaglandins.
Applications
UsesSC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures.
UsesSC 19220 is a selective EP1receptor antagonist.
Suppliers19 total
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
Aladdin Scientific[email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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