Basic information
- CAS
464-92-6- Standard SMILES
CC1CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(CO)C5CCC43C)C2C1C- InChIKey
JXSVIVRDWWRQRT-UHFFFAOYSA-N- Molecular formula
- C30H48O5
- Average molar mass
- 488.7 g/mol
- Monoisotopic mass
- 488.35017463
Overview
asiatic acid has been reported in Weigela subsessilis, Centella erecta, and other organisms with data available.
Names & identifiers
- Preferred name
- 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- IUPAC
- 10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
- English name
- Asiatic acid
- Molecular formula
- C30H48O5
- Molecular weight
- 488.7
Names & synonyms
10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acidRefChem:10571832,24-Dihydroxyursolic acidUrs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2alpha,3beta,4beta)-143839-02-5Esculentic acid (Diplazium)2,3,23-trihydroxyurs-12-en-28-oic acidSCHEMBL136639orb31713362alpha,23-Dihydroxyursolic acidHMS5080K22DEA97474
Show more names
ASIATICA ACID2,3,23-TRIHYDROXY-12-URSEN-28-OIC ACIDNSC 166063ASIATIC ACIDAsiantic acidASIATIC ACID(P)DaMMarolic acidAsiatic acid-RMAsiatic Acid >Snow oxalic acid
MFCD20529097NSC166063STK801367AKOS005613009AC-6027NCGC00389422-01VS-02270DB-051381
Properties
Computed structural properties
- XLogP
- 5.7
- Topological polar surface area
- 98 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 2
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 930
Experimental & physicochemical properties
Melting Point270 °C
Physical DescriptionSolid
Physicochemical properties
- Melting point
- 325 · 325-330 °C(lit.)
- Boiling point
- 609.4 · 609.4±55.0 °C(Predicted)
- Density
- 1.18 · 1.18±0.1 g/cm3(Predicted)
- RTECS
- 9580000 · YU9580000
- storage temp.
- 2 · 2-8°C
- solubility
- 1 mg/mL, · methanol: soluble1mg/mL, clear, colorless
- form
- powder
- pka
- 4.66 · 4.66±0.70(Predicted)
- color
- white
- biological source
- Centella asiatica
- Water Solubility
- Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- hs_code
- 29181990
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H413
- REACH Registrations
- Active
- Precautionary statements
- P501-P273
- Hazardous Substances Data
- 464-92-6(Hazardous Substances Data)
Chemistry & industry
Pharmacology
Cellular LocationsExtracellular
Applications
Useswound healing, experimental carcinogen
UsesAsiatic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Asiatic Acid is a neuroprotectant and induces of apoptosis in HepG2 human hepatoma cells.
UsesAsiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. It is a starting material for asiatic acid derivative synthesis for use as anticancer agents, glycogen phosphorylase inhibitors and and hepatoprotectants.
General DescriptionAsiatic acid is a naturally occurring pentacyclic triterpenoid, obtained from Centella asiatica.
Upstream & downstream products
Upstream raw materials
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
成都普瑞法科技开发有限公司+86-028-82633397 18982077548 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
武汉创硕化工科技有限公司180-62205282 18062205282 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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