Basic information
- CAS
20424-00-4- Standard SMILES
CCC(=O)OC1(C(C)=O)CCC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC21C- InChIKey
DRSFVGQMPYTGJY-UHFFFAOYSA-N- Molecular formula
- C24H32O5
- Average molar mass
- 400.5 g/mol
- Monoisotopic mass
- 400.22497412
Names & identifiers
- Preferred name
- 11-Hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoate
- IUPAC
- (17-acetyl-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl) propanoate
- English name
- Deprodone propionate
- Molecular formula
- C24H32O5
- Molecular weight
- 400.51
Names & synonyms
11-hydroxy-3,20-dioxopregna-1,4-dien-17-yl propanoateDTXSID70942600EclarRD 20000DesoloneAllomidonEinecs 243-810-1deprodone propionateDeprodone 17-propionateChromafenozide Impurity 2Deprodone propionate (JAN)Deprodone propionate (RD20000)
Database identifiers
- CAS
20424-00-4- PubChem CID
- 2991
- DTXSID
DTXSID70942600
Properties
Computed structural properties
- XLogP
- 3.6
- Topological polar surface area
- 80.7 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 29
- Formal charge
- 0
- Complexity
- 825
Physicochemical properties
- Melting point
- 227 · 227-229 °C
- Boiling point
- 540.6 · 540.6±50.0 °C(Predicted)
- Density
- 1.2 · 1.20±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 250 mg/mL · DMSO: 250 mg/mL (624.20 mM)
- form
- Solid
- pka
- 14.09 · 14.09±0.70(Predicted)
- color
- White to off-white
- FDA UNII
- 377 ZHW5OE · S377ZHW5OE
Chemistry & industry
Applications
DescriptionDeprodone propionate is a new topical antiinflammatory corticosteroid. In animal studies, it exhibited an extremely low skin irritation rate. Another potential use is as an antiasthmatic agent.
UsesEster of 21-Deoxyprednisolone 17α-Propionate is a topical antiinflammatory agent.
Upstream & downstream products
Upstream raw materials
Suppliers20 total
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
InvivoChem中国13549236410 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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