Basic information
- CAS
59859-58-4- Standard SMILES
COc1ccc(OC[C@H]2CN(C)CC[C@@H]2c2ccccc2)cc1- InChIKey
OJSFTALXCYKKFQ-YLJYHZDGSA-N- Molecular formula
- C20H25NO2
- Average molar mass
- 311.4 g/mol
- Monoisotopic mass
- 311.18852904
Overview
Femoxetine is a member of piperidines.
Names & identifiers
- Preferred name
- (+)-Femoxetine
- IUPAC
- (3R,4S)-3-[(4-methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidine
- English name
- Femoxetine
- Molecular formula
- C20H25NO2
- Molecular weight
- 311.42
Names & synonyms
Femoxetine59859-58-4Femoxetina(+)-FemoxetineFemoxetinum8Y719ZLX8CDTXSID70208576Piperidine, 3-((4-methoxyphenoxy)methyl)-1-methyl-4-phenyl-, (3R-trans)-femoxitineRefChem:140087DTXCID20131067trans-3-((4-methoxyphenoxy)methyl)-1-methyl-4-phenylpiperidine
Show more names
Malexil(3R)-1-Methyl-3α-(4-methoxyphenoxymethyl)-4β-phenylpiperidine(3R)-3α-[(4-Methoxyphenoxy)methyl]-1-methyl-4β-phenylpiperidinePiperidine, 3-[(4-methoxyphenoxy)methyl]-1-methyl-4-phenyl-, (3R,4S)-
trans-(+)-3-((4-methoxyphenoxy)methyl)-1-methyl-4-phenylpiperidineFemoxetine [INN](3R,4S)-3-[(4-methoxyphenoxy)methyl]-1-methyl-4-phenylpiperidineFemoxetinum [INN-Latin]Femoxetina [INN-Spanish]UNII-8Y719ZLX8CCHEMBL94739(+)-trans-3-((p-Methoxyphenoxy)methyl)-1-methyl-4-phenylpiperidine
Database identifiers
- CAS
59859-58-4- PubChem CID
- 3012003
- DTXSID
Properties
Computed structural properties
- XLogP
- 4
- Topological polar surface area
- 21.7 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 335
Physicochemical properties
- Boiling point
- 437.9 · 437.9±35.0 °C(Predicted)
- Density
- 1.055 · 1.055±0.06 g/cm3(Predicted)
- pka
- 8 · 8+-.0.10(Predicted)
- FDA UNII
- 8 Y719ZLX8C · 8Y719ZLX8C
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Compounds that specifically inhibit the reuptake of serotonin in the brain.
Applications
Uses(+)-Femoxetine is an antidepressant drug.
Suppliers6 total
LGM Pharma1-(800)-881-8210 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
上海阿摩尔生物科技有限公司13370042665 18916960931 · [email protected]
Additional notes
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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