Basic information
- CAS
164178-54-5- Standard SMILES
CCOC(=O)CCCn1nnnc1-c1ccc2c(c1)[C@@H](Oc1ccc(=O)[nH]n1)[C@](C)(O)C(C)(C)O2- InChIKey
NMOVZVDTGJSEMC-OFNKIYASSA-N- Molecular formula
- C23H28N6O6
- Average molar mass
- 484.5 g/mol
- Monoisotopic mass
- 484.20703263
Overview
Mazokalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Mazokalim is a potassium channel activator, antihypertensive. Mazokalim has a monoisotopic molecular weight of 484.21 Da.
Names & identifiers
- Preferred name
- Mazokalim
- IUPAC
- ethyl 4-[5-[(3S,4R)-3-hydroxy-2,2,3-trimethyl-4-[(6-oxo-1H-pyridazin-3-yl)oxy]-4H-chromen-6-yl]tetrazol-1-yl]butanoate
- English name
- Mazokalim
- Molecular formula
- C23H28N6O6
- Molecular weight
- 484.51
Names & synonyms
Mazokalim164178-54-5Mazokalim [INN:BAN]UNII-K3N608EC7LK3N608EC7LMAZOKALIM [INN]DTXSID20167720Ethyl 5-((3S,4R)-4-((1,6-dihydro-6-oxo-3-pyridazinyl)oxy)-3-hydroxy-2,2,3-trimethyl-6-chromanyl)-1H-tetrazole-1-butyratemazokalimumRefChem:156030DTXCID4090211ethyl 4-[5-[(3S,4R)-3-hydroxy-2,2,3-trimethyl-4-[(6-oxo-1H-pyridazin-3-yl)oxy]-4H-chromen-6-yl]tetrazol-1-yl]butanoate
Show more names
1H-Tetrazole-1-butanoic acid, 5-[(3S,4R)-4-[(1,6-dihydro-6-oxo-3-pyridazinyl)oxy]-3,4-dihydro-3-hydroxy-2,2,3-trimethyl-2H-1-benzopyran-6-yl]-, ethyl ester
SCHEMBL1230354SCHEMBL8885052CHEMBL2105166NS00124776Q27281911Ethyl 4-(5-{(3S,4R)-3-hydroxy-2,2,3-trimethyl-4-[(6-oxo-1,6-dihydropyridazin-3-yl)oxy]-3,4-dihydro-2H-1-benzopyran-6-yl}-1H-tetrazol-1-yl)butanoate
Database identifiers
- CAS
164178-54-5
Properties
Computed structural properties
- XLogP
- 0.9
- Topological polar surface area
- 150 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 9
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 865
Physicochemical properties
- Density
- 1.41 · 1.41±0.1 g/cm3(Predicted)
- pka
- 10.3 · 10.30±0.40(Predicted)
- FDA UNII
- 3 N608EC7L · K3N608EC7L
Chemistry & industry
Applications
UsesMazokalim is used for surface topogs. for nontoxic bioadhesion control.
Suppliers4 total
2A PharmaChem USA[email protected]
Leancare Ltd.[email protected]
Lanospharma Laboratories Co.,Ltd13440048448 · [email protected]
3B Scientific Corporation[email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…