Basic information
- CAS
1165-48-6- Standard SMILES
COc1ccc2c(=O)c(C)c(-c3ccccc3)oc2c1CN(C)C- InChIKey
ZXFQRFXLFWWKLX-UHFFFAOYSA-N- Molecular formula
- C20H21NO3
- Average molar mass
- 323.4 g/mol
- Monoisotopic mass
- 323.15214353
Overview
Dimefline is an ether and a member of flavonoids.
Names & identifiers
- Preferred name
- Dimefline
- IUPAC
- 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenylchromen-4-one
- English name
- Dimefline HCL
- Molecular formula
- C20H21NO3
- Molecular weight
- 323.39
Names & synonyms
DIMEFLINEDimeflinMalivan1165-48-6ReanimilDimeflinaDimeflinum9WII5M0DU3NSC-1698698-((Dimethylamino)methyl)-7-methoxy-3-methylflavone8-Dimethylaminomethyl-7-methoxy-3-methyl-2-phenylchromoneN-(7-Methoxy-3-methyl-4-oxo-2-phenyl-4H-chromen-8-yl)methyl-N,N-dimethylamine
Show more names
DW-62DimelfinRemeflinREC-7/0267Dimefline HCLDimefline HCL USP/EP/BP
Flavone, 8-(dimethylaminomethyl)-7-methoxy-3-methyl-4H-1-Benzopyran-4-one, 8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenyl-4H-1-Benzopyran-4-one, 8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-DTXSID00482683-Methyl-7-methoxy-8-dimethylamino-methylflavone8-[(Dimethylamino)methyl]-7-methoxy-3-methylflavone8-((dimethylamino)methyl)-7-methoxy-3-methyl-2-phenyl-4H-chromen-4-oneRefChem:134145
Database identifiers
- CAS
1165-48-6- PubChem CID
- 3078
- DTXSID
DTXSID0048268
Properties
Computed structural properties
- XLogP
- 3.6
- Topological polar surface area
- 38.8 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 493
Experimental & physicochemical properties
LogP1.93
Other Experimental PropertiesDECOMP @ 213-214 °C; CRYSTALS FROM ALCOHOL + ETHER /DIMEFLINE HYDROCHLORIDE/
Physicochemical properties
- Melting point
- 109.5 °C · 109.5°C
- Boiling point
- 461.86 °C · 461.86°C (rough estimate)
- Density
- 1.1773 · 1.1773 (rough estimate)
- refractive index
- 1.58 · 1.5800 (estimate)
- pka
- 8.2 · 8.20±0.28(Predicted)
- FDA UNII
- 9 WII5M0DU3 · 9WII5M0DU3
- ATC code
- 7 AB08 · R07AB08
- Hazardous Substances Data
- 1165 · 1165-48-6(Hazardous Substances Data)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Hazardous Substances Data
- 1165-48-6(Hazardous Substances Data)
Chemistry & industry
Pharmacology
ATC Code
R - Respiratory system
QR - Respiratory system
Uses & manufacturing
UsesRESPIRATORY STIMULANT
Methods of ManufacturingDA RE ET AL, ARZNEIMITTEL-FORSCH 10, 800 (1960); BRITISH PATENT 882,537 CORRESP TO DA RE, US PATENT 3,147,258 (1961, 1964 BOTH TO RECORDATI).
Formulations/PreparationsREC 7-0267, REMEFLIN. /DIMEFLINE HYDROCHLORIDE/
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionChEBI: Dimefline is an ether and a member of flavonoids.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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