HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stevisalioside A
stevisalioside A
Identifiers & Physical Properties
| CAS No. | 142934-44-9 |
|---|---|
| Molecular formula | C35H50O15 |
| Average molar mass | 710.8 g/mol |
| Monoisotopic mass | 710.31497088 g/mol |
| SMILES | C=C1CC23CCC4C(C)(C(=O)OC5OC(CO)C(OC6OCC(O)C(O)C6O)C(OC(C)=O)C5OC(C)=O)CCCC4(C)C2C(O)C1C(=O)C3 |
| InChIKey | DYJKTUJXLVAKKU-UHFFFAOYSA-N |
| PubChem CID | 3083369 |
| DTXSID | DTXSID30931691 |
Chemical & Physical Properties
| XLogP | 0.1 |
|---|---|
| Topological polar surface area | 225 |
| Hydrogen bond donors | 5 |
| Hydrogen bond acceptors | 15 |
| Rotatable bonds | 10 |
| Heavy atoms | 50 |
| Formal charge | 0 |
| Complexity | 1,390 |
Applications & Uses
Uses
Stevisalioside A (Compound 2) can be isolated from Stevia serrata roots. Stevisalioside A is an orally active antidiabetic agent. Stevisaliosides A inhibits PTP1B (IC50: 526.8 μM). Stevisalioside A reduces blood glucose levels and the postprandial peak in oral glucose and insulin tolerance tests in Streptozotocin (HY-13753) induced hyperglycemic mice[1].