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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 3083370Generated: November 1, 2026

Men 10354

MEN 10354

https://huagongshe.com/en/chemical/3083370

Men 10354 molecular structure

Identifiers & Physical Properties

CAS No.142959-76-0
Molecular formulaC37H46N8O9
Average molar mass746.8 g/mol
Monoisotopic mass746.33877507 g/mol
SMILESC=C(C)C[C@@H](C=O)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(=O)O
InChIKeyXEZFPYHBVYERSG-RKHRJCDKSA-N
PubChem CID3083370
DTXSIDDTXSID70162240

Chemical & Physical Properties

XLogP-2.4
Topological polar surface area285
Hydrogen bond donors9
Hydrogen bond acceptors10
Rotatable bonds22
Heavy atoms54
Formal charge0
Complexity1,370

Applications & Uses

Description

MEN-10354 is a less potent and less selective NK-2 tachykinin receptor antagonist compared to the linear analog, R 396.